Abstract:

Objective To understand the improvement of respiratory and systemic symptoms and signs of pulmonary tuberculosis patients treated with modified Baihe Gujin decoction，and to provide evidence ⁃ based evidence for multidisciplinary treatment of tuberculosis. Methods A total of 92 patients with newly diagnosed pulmonary tuberculosis who came to our hospital from June 2018 to December 2021 were selected as the research objects. 50 patients in the observation group and 42 patients in the control group were treated for 4 weeks with anti ⁃tuberculosis treatment and anti ⁃tuberculosis combined with modified Baihe Gujin decoction. The changes of symptoms and signs such as cough，expectoration，sore throat，chest tightness，shortness of breath，thirst，mental fatigue，fatigue and anorexia were observed before and after 4 weeks treatment，and the severity was recorded as none，mild，moderate and severe. Changes were analyzed，and the c2 test was used to compare and analyze the difference in improvement rate between the observation group and the control group，as well as between male and female in the observation group. Results The rates of cough，expectoration，sore throat，chest tightness，shortness of breath，thirst，mental fatigue，fatigue，anorexia and overall improvement in the observation group were 100%， 100%，92.00%，90.00%，78.00%，96.00%，84.00%，76.00%，96.00%，and 90.22%，respectively. The control group were 83.33%，90.48%，76.19%，45.24%，69.05%，71.43%，59.52%，64.29%，64.29%，69.31%，respectively. Except for expectoration，shortness of breath and fatigue，the comparison of the rates between the observation group and the control group was statistically significant（P < 0.05）. Comparing 24 males and 26 females in the observation group，the improvement rates for males were 100% ，100% ，95.83% ，91.67% ，75.00% ，100% ， 91.67%，83.33%，91.67%，and 92.13%，respectively. For females，the rates were 100%，100%，88.46%，88.46%， 80.77%，92.31%，76.92%，69.23%，100%，and 88.46%，respectively. The difference in rates between the two sexes was not statistically significant（P > 0.05）. Conclusion Modified Baihe Gujin Decoction can significantlyimprove the respiratory and systemic symptoms and signs of pulmonary tuberculosis patients，and it is suitable for both men and women. 

Key words:

pulmonary tuberculosis, anti ?tuberculosis chemotherapy, modified Baihe Gujin decoc? tion, symptoms and signs