The Journal of Practical Medicine ›› 2022, Vol. 38 ›› Issue (3): 380-384.doi: 10.3969/j.issn.1006⁃5725.2022.03.023

• Reviews • Previous Articles     Next Articles

Application and research progress of stem cells in repair of skull defects

CAO Zhiwei*，SHAO Guo，ZHAO Zhijun，ZHANG Chunyang.   

  1. Baotou Medical College of Inner Mongolia University of Science and Technology，Baotou 014000，China；*Department of Neurosurgery，the First Affiliated Hospital of Baotou Medical College of In⁃ner Mongolia University of Science and Technology，Baotou 014000，China；*Institute of Neurosurgical Diseases，Baotou Medical College（Translational Medicine），Baotou 014000，China；*Inner Mongolia Autonomous RegionBone Tissue Regeneration and Damage Repair Engineering Technology Center，Baotou 014000，China

  • Online:2022-02-10 Published:2022-02-10
  • Contact: ZHANG Chunyang E⁃mail：zhangchunyang_1964@aliyun.com

Abstract:

Skull defects is a common and important clinical condition in neurosurgery. Using the osteogenicproperties of stem cells to repair bone defects of critical size has become the focus of attention. Application ofvarious stem cells has presently made significant progress in bone tissue engineering. However，how to improve theimplantation rate and survival rate of stem cells is the key to this repair method. Therapies with stem cells for skulldefects have been proven feasible in animal studies，providing a new way for further clinical research. Stem celltransplantation is still the most promising procedure for repairing skull defects.

Key words: stem cell, transplantation, skull defect, skull repair