实用医学杂志 ›› 2022, Vol. 38 ›› Issue (6): 763-766.doi: 10.3969/j.issn.1006⁃5725.2022.06.022

• 临床研究 • 上一篇    下一篇

硫酸吗啡缓释片联合针灸对癌痛患者镇痛效果及生存质量的影响

李非铭 赵俊莺 方海博 舒雅   

  1. 西安医学院第一附属医院疼痛科(西安 710077)

  • 出版日期:2022-03-25 发布日期:2022-03-25
  • 通讯作者: 舒雅 E⁃mail:465380723@qq.com

Analysis of the analgesic effect and quality of life in cancer patients who receiving morphine sulfate sustained ⁃release tablets combined with acupuncture

LI Feiming,ZHAO Junying,FANG Haibo,SHU Ya.   

  1. Department of Pain Treatment,the First Affiliated Hospital of Xi ,Xi,China

  • Online:2022-03-25 Published:2022-03-25
  • Contact: SHU Ya E⁃mail:465380723@qq.com

摘要:

目的 观察硫酸吗啡缓释片联合针灸治疗癌症疼痛患者的临床效果。方法 选取 2020 1 月至 2021 6 月在我院收治的癌痛患者 70 例,随机分为对照组和观察组,每组 35 例。对照组采用硫酸 吗啡缓释片治疗,观察组在对照组治疗基础上采用针灸治疗足三里、百会穴、阿是穴。治疗 14 d 后采用 NRS,KPS 对患者疼痛情况和生存质量进行评价,并分析治疗后每日药物使用量以及疼痛缓解率和不良反 应发生率。结果 观察组患者总有效率为 91.43%,高于对照组 82.86%(Z = 12.120,P = 0.007),治疗后观 察组患者较对照组 NRS 评分降低,KPS 评分升高(P < 0.05)。与治疗前相比,观察组患者硫酸吗啡缓释片 日用量基本维持,而对照组患者药物使用量显著增加。不良反应发生率观察组为 48.57%,对照组为 77.14%。结论 针灸联合硫酸吗啡缓释片缓解癌痛,提高患者生存质量,降低不良反应发生率,安全性 高,值得临床推广。

关键词: 癌痛,  , 硫酸吗啡缓释片,  , 针灸,  , 镇痛

Abstract:

Objective The study aimed to observe the clinical effect of morphine sulfate sustained⁃release tablets combined with acupuncture on cancer pain. Methods A total of seventy patients with cancer pain admitted to our hospital from January 2020 to June 2021 were randomly divided into control group and observation group. There were 35 cases in each group respectively. The control group was treated with morphine sulfate sustained ⁃ release tablets and the observation group with acupuncture and moxibustion at Zusanli,Baihui and Ashi points. NRS and KPS were applied to evaluate the pain and quality of life. The daily drug use,pain relief rate and incidence of adverse reactions after treatment were analyzed. Results The effective rate in observation group was 91.43%,which was higher than 82.86% in control group(Z = 12.120,P = 0.007). After treatment,the NRS score and KPS score in observation group were lower than those in control group(P < 0.05). Compared with the data before treatment,the daily dosage of morphine sulfate sustained ⁃ release tablets in the observation group was basically maintained,while the dosage of drugs in the control group was significantly increased. The incidence of adverse reactions was 48.57% in observation group and 77.14% in control group. Conclusion Acupuncture and moxibustion combined with morphine sulfate sustained⁃release tablets could relieve cancer pain,improve the quality of life of patients,reduce the incidence of adverse reactions and had high safety,which was worthy of clinical promotion.

Key words:

cancer pain, morphine sulfate extended?release tablets, acupuncture, analgesia