实用医学杂志 ›› 2022, Vol. 38 ›› Issue (8): 917-922.doi: 10.3969/j.issn.1006⁃5725.2022.08.001

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重症肌无力治疗的中外指南对比及解析

王可1 徐鹏2 张影2 张艺缤1 嵇鑫陈1 王健2   

  1. 1 长春中医药大学(长春 130117);2 长春中医药大学附属医院(长春 130021)

  • 出版日期:2022-04-25 发布日期:2022-04-25
  • 通讯作者: 王健 E⁃mail:jian⁃w222@163.com
  • 基金资助:

    吉林省科技发展计划项目(编号:20190905005SF); 吉林省科技发展计划项目(编号:20180311025YY);吉林省中医 药科技项目(编号:2020164);吉林省卫生健康技术创新项目(编 号:20191056);吉林省自然科学基金(编号:20210101212JC);吉 林省中医药科技项目(编号:2022035);吉林省教育科学“十四五” 规化重点课题(编号:ZD21048)

Comparative analysis of Chinese and foreign guidelines for the treatment of myasthenia gravis

WANG Ke*,XU Peng,ZHANG Ying,ZHANG Yibin,JI Xinchen,WANG Jian.    

  1. Changchun University of Chinese Medi⁃ cine,Changchun 130117,China

  • Online:2022-04-25 Published:2022-04-25
  • Contact: WANG Jian E⁃mail:jian⁃w222@163.com

摘要:

目前尚无根治重症肌无力的特效药,且该病因分型多样、受病人群多样,故其治疗选择也不 同,长短期疗效、预后及安全性也存在差异。为给患者选择安全有效的用药方案,本文将结合中外相关研 究,对 2020 年中国免疫学会和美国重症肌无力基金会发布的重症肌无力最新指南,进行对比分析,并对重 症肌无力常用治疗进行阐述,旨在为临床医生提供更多参考。

关键词:

重症肌无力, 指南, 治疗, 胸腺切除术, 靶向生物制剂

Abstract:

At present,there is no specific drug for the radical treatment of myasthenia gravis. The thera⁃ pies vary with different etiology and population of patients as well,with discrepancies in long⁃term and short⁃term efficacy,prognosis and safety. In order to select a safe and effective medication regimen for the patients,this paper reviews the relevant domestic and foreign studies and compares the latest guidelines of myasthenia gravis issued by the Chinese Society for Immunology and the Myasthenia Gravis Foundation of America in 2020,aiming to provide surgeons with more references for the treatment of myasthenia gravis.

Key words:

myasthenia gravis, guidelines, treatment, thymotomy, targeted biologics