实用医学杂志 ›› 2023, Vol. 39 ›› Issue (7): 910-913.doi: 10.3969/j.issn.1006⁃5725.2023.07.021

• 中医药现代化 • 上一篇    下一篇

理冲汤联合生化汤颗粒治疗气虚血瘀型子宫腺肌病的效果及对机体卵巢功能的影响 

侯爱贞 王利平 杜鹃 徐玉慧 张庆    

  1. 开封市中医院妇科(河南开封475001)

  • 出版日期:2023-04-10 发布日期:2023-04-10
  • 基金资助:
    开封市科技攻关计划项目(编号:2003099)

Effect of Lichong Decoction combined with Shenghua Decoction(granules)on both adenomyosis of qi defi⁃ ciency and blood stasis type and ovarian function

HOU Aizhen,WANG Liping,DU Juan,XU Yuhui,ZHANG Qing.   

  1. Department of Gynecology,Kaifeng Hospital of Traditional Chinese Medicine,Kaifeng 475001,China

  • Online:2023-04-10 Published:2023-04-10

摘要:

目的 探究理冲汤联合生化汤颗粒治疗气虚血瘀型子宫腺肌病的效果及对机体卵巢功能 的影响,以期为子宫腺肌病提供中医治疗方案。方法 100 例子宫腺肌症患者根据 1∶1 简单分配原则 分为中医组与对照组,各 50 例,对照组给予放置左炔诺孕酮宫内缓释系统(LNG⁃IUS)治疗,中医组在对照 组治疗的基础上给予理冲汤联合生化汤颗粒治疗,两组都治疗观察3个月,记录治疗效果及其对机体卵巢 功能的影响。结果 治疗后中医组的总有效率(98.0 %)显著高于对照组(86.0 %)(P < 0.05);两组治疗后 VAS 评分都显著低于治疗前(P < 0.05),中医组也明显低于对照组(P < 0.05);两组治疗前后的血清黄 体生成素(LH)和卵泡刺激素(FSH)含量在组内与组间对比差异无统计学意义(P > 0.05);两组治疗后的 血清超氧化物歧化酶(SOD)、过氧化氢酶(CAT)含量都高于治疗前(P < 0.05),中医组与对照组相比也明 显提高(P < 0.05)。结论 理冲汤联合生化汤颗粒治疗气虚血瘀型子宫腺肌病能提高治疗效果,且不会 影响机体的卵巢功能,还可促进血清SOD、CAT 的释放,促进缓解痛经症状。

关键词:

理冲汤, 生化汤颗粒, 气虚血瘀型, 子宫腺肌病, 超氧化物歧化酶, 卵巢功能

Abstract:

Objective To explore the effects of Lichong Decoction combined with Shenghua Decoction (granules)on both adenomyosis of qi deficiency and blood stasis type and ovarian function in order to provide tradi⁃ tional Chinese medicine treatment plan for adenomyosis. Methods A total of 100 patients with uterine adenomyosis were equally divided into TCM group and control group according to the 1∶1 simple allocation principle. The control group and the TCM group were treated with levonorgestrel intrauterine sustained⁃release system(LNG⁃IUS and biochemical soup pellets on the basis of the control group for 3 months. Its effect on the body ovarian function was investigated. Results After treatment,the total effective rate in the traditional Chinese medicine group were 98.0%,which were significantly different from 86.0% in the control group(P < 0.05). The VAS scores of dysmen⁃ orrhea in both groups after treatment were significantly lower than those before treatment(P < 0.05),and those in the traditional Chinese medicine group were significantly lower than those in the control group(P < 0.05). There were no significant differences in serum LH and FSH levels between the two groups before and after treatment(P > 0.05). The serum levels of SOD and CAT in both groups after treatment were higher than those before treatment (P < 0.05),and the levels in the traditional Chinese medicine group were significantly higher than those in the control group(P < 0.05). Conclusion Lichong decoction combined with Shenghua decoction granules for treating adenomyosis with qi deficiency and blood stasis can not only improve the therapeutic effect without affecting the body′ s ovarian function,but also promote the release of serum SOD and CAT and the relief of dysmenorrhea symptoms.

Key words:

Lichong Decoction, Shenghua Decoction(granules), qi deficiency and blood stasis type, adenomyosis, superoxide dismutase, ovarian function