实用医学杂志 ›› 2023, Vol. 39 ›› Issue (7): 914-918.doi: 10.3969/j.issn.1006⁃5725.2023.07.022

• 综述 • 上一篇    下一篇

肠道微生物组在麻醉学领域的研究现状及进展

ZHANG Weiyi,SONG Xinye,LUAN Yong.   

  1. 大连医科大学附属第一医院麻醉科(辽宁大连 116011)

  • 出版日期:2023-04-10 发布日期:2023-04-10
  • 通讯作者: 栾永 E⁃mail:cclyyly@163.com
  • 基金资助:
    国家自然科学基金项目(编号:LZ2020028)

Gut microbiome in anesthesiology:a literate review

张魏怡 宋辛叶 栾永
  

  1. Department of Anesthesiology,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China 

  • Online:2023-04-10 Published:2023-04-10
  • Contact: LUAN Yong E⁃mail:cclyyly@163.com

摘要:

近年来,人类微生物组在健康和疾病中的研究为临床医学的许多领域带来了新的启示。新的研究表明,肠道微生物组与麻醉剂和镇痛剂的作用、围手术期结局、重症监护和术后疼痛等不同临床领域均有相互作用及潜在的临床应用。然而,人们对肠道微生物组在麻醉和疼痛中的作用知之甚少,仍有广阔的研究空间。为此本文回顾了人类肠道微生物组的基本概念、影响宿主的可能机制和干预微生物用于治疗的方式方法,概述了将肠道微生物组与麻醉学相关领域联系起来的证据。

关键词: 肠道微生物组, 麻醉学, 术后疼痛

Abstract:

In recent years,the research on the heath and disease of the human microbiome has shed new light on many fields of clinical medicine.New research shows that gut microbiome is correlated with anesthetics and analgesics,perioperative outcomes,intensive care and postoperative pain,indicating potential clinical applica⁃ tions in different clinical fields. However,little is known about the role of gut microbiota in anesthesia and pain. In this paper,we have reviewed the basic concept of human gut microbiome,the possible mechanisms that affect hosts and the ways and means to intervene microorganisms for treatment,and summarized the evidence that gut microbiome is linked with anesthesia.

Key words:

gut microbiome, anesthesiology, postoperative pain