实用医学杂志 ›› 2022, Vol. 38 ›› Issue (24): 3065-3071.doi: 10.3969/j.issn.1006⁃5725.2022.24.008

• 临床研究 • 上一篇    下一篇

颞部直切口小骨窗锁孔开颅手术治疗基底节出血的疗效 

杨亚飞 吴炳山 高鹏 代兴亮 程宏伟    


  1. 安徽医科大学第一附属医院神经外科(合肥230022)

  • 出版日期:2022-12-25 发布日期:2022-12-25
  • 通讯作者: 代兴亮 E⁃mail:daixingliang@ahmu.edu.cn;程宏伟 E⁃mail:hongwei.cheng@ahmu.edu.cn
  • 基金资助:
    国家自然科学基金项目(编号:81702457)

Analysis of the curative effect of temporal straight incision small bone window keyhole craniotomy in the treatment of basal ganglia hemorrhage

YANG Yafei,WU Bingshan,GAO Peng,DAI Xingliang,CHENG Hon⁃ gwei.   

  1. Department of Neurosurgery,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China

  • Online:2022-12-25 Published:2022-12-25
  • Contact: DAI xingliang E⁃mail:daixingliang@ahmu.edu.cn;CHENG Hongwei E⁃mail:hongwei. cheng@ahmu.edu.cn

摘要:

目的 探讨颞部直切口小骨窗锁孔开颅手术治疗基底节出血的疗效。方法 回顾性分析 安徽医科大学第一附属医院神经外科 2018 8 月至 2022 2 月收治的 72 例行开颅手术的基底节出血 患者。其中 33 例患者行锁孔开颅手术(观察组),39 例患者行大骨瓣开颅手术(对照组),比较两者手术 效果,包括手术时间、血肿清除比例、术后并发症、住院时长、住院费用,出院时的意识状态及预后情况。 结果 观察组与对照组对比结果提示,两组开颅时间分别为(17.03 ± 4.60)min 和(38.18 ± 8.49)min,手术 时间分别为(130.73 ± 44.70)min 和(211.10 ± 60.14)min,血肿清除率分别为(92.88 ± 5.33)%和(87.00 ± 15.00)%,住院时间分别为(16.88 ± 8.02)d 和(22.79 ± 11.23)d,硬膜外血肿发生比例分别为 15.15% 41.03%,颞肌水肿发生比例分别为 12.12% 41.03%,住院费用观察组(10.47 ± 4.35)万元,对照组(13.08 ± 5.30)万元,上述指标的差异均有统计学意义(P < 0.05)。观察组和对照组的 ICU 入住时间[(7.91 ± 5.40)d 和(9.38 ± 8.34)d]、机械通气时间[(6.06 ± 4.80)d 和(6.90 ± 5.64)d]、出院时 GCS 评分[(12.38 ± 2.62)和 12.03 ± 2.40)]、颅内感染比例(0%和5.13%)、术后肺部感染发生比例(54.55%和51.28%)、术后再出血比例 3.03% 5.13%)和术后深静脉血栓发生比例(12.12% 7.69%),两组效果差异无统计学意义(P > 0.05); 观察组和对照组术后 3 月日常活动能力评分(ADH)评估中功能正常比例为 6.25% 2.70%、功能轻度损害 比例为 25.00% 24.32%、功能中度损害比例为 34.48% 32.43%、功能重度损害比例为 28.13% 32.43% 死亡比例 6.25% 8.11%,两组预后差异无统计学意义(P > 0.05)。结论 颞部直切口小骨窗锁孔开颅治 疗基底节出血创伤小,开颅时间短,清除血肿率高,显著缩短手术时间和住院时间,减少并发症,降低住院 费用,具有较好的临床疗效,安全性较高,具备临床应用价值。

关键词:

基底节出血, 锁孔手术, 直切口, 疗效

Abstract:

Objective To investigate the effect of temporal straight incision small bone window keyhole craniotomy in the treatment of basal ganglia hemorrhage. Methods A retrospective analysis was performed on 72 patients with basal ganglia hemorrhage who underwent craniotomy in the Department of Neurosurgery of the First Affiliated Hospital of Anhui Medical University from August 2018 to February 2022.There were 33 patients who had keyhole craniotomy(observation group)and 39 patients who had large⁃scale craniotomy(control group). The surgical outcomes of the two groups were compared,including operation time,hematoma clearance ratio,postopera⁃ tive complications,and hospitalization,duration,hospitalization costs,state of consciousness at discharge,and prognosis. Results The comparison between the observation group and the control group showed that the craniotomy time in the two groups was(17.03 ± 4.60)min and(38.18 ± 8.49)min,respectively,the operation time was (130.73 ± 44.70)min and(211.10 ± 60.14)min,respectively. The clearance rates were(92.88 ± 5.33)% and (87.00 ± 15.00)%,respectively. The length of hospital stay was(16.88 ± 8.02)d and(22.79 ± 11.23)d,respec⁃ tively. The incidence of epidural hematoma was 15% and 41%,respectively. The incidence of muscle edema was 12% and 41%,respectively. The hospitalization expenses of the observation group were(10.47 ± 4.35)ten thousandyuan,and the control group was(13.08 ± 5.30)ten thousand yuan. The difference of the above indicators was statistically significant(P < 0.05). In the observation group and the control group,the ICU stay time was(7.91± 5.40)d and(9.38 ± 8.34)d,the mechanical ventilation time was(6.06 ± 4.80)d and(6.90 ± 5.64)d,the GCS score at discharge was(12.38 ± 2.62)and(12.03 ± 2.40),the proportion of intracranial infection 0% and 5% and the incidence rate of pulmonary infection was 55% and 51%,the incidence rate of postoperative rebleeding was 3% and 5%,and the incidence rate of postoperative deep vein thrombosis was 12% and 8%. There was no significant difference(P>0.05). In the ADH assessment of the observation group and the control group at 3 months after operation,the proportion of normal function was(6.2%)and(2.7%),the proportion of mild function impair⁃ ment was(25.0%)and(24.3%),the proportion of moderate function impairment was(34.4%)and(32.4%), and the proportion of severe function impairment was(28.1%)and(32.4%),death rate(6.3%)and(8.2%). There was no significant difference in prognosis between the two groups(P > 0.05). Conclusion In the treatment of basal ganglia hemorrhage,a temporal straight incision small bone window keyhole craniotomy has less trauma,a shorter craniotomy time,a high rate of hematoma removal,a significantly shorter operation time and hospitalization time,fewer complications,and lower hospitalization costs. It has a high safety and clinical application value,as well as good clinical efficacy.

Key words:


basal ganglia hemorrhage, keyhole surgery, straight incision, curative effect