关键词:

脊髓损伤, 脑机接口训练, 下肢运动功能, 步行功能

Abstract:

Objective To investigate the effect of brain⁃computer interface（BCI）training on the improve⁃ ment of lower limb motor function in patients with spinal cord injury. Methods Sixty patients with spinal cord injury who were treated in the Department of Rehabilitation Medicine of our hospital were selected and divided into control group and study group，with 30 cases in each group. The modified Barthel index（MBI）was used to evaluate the activities of daily living（ADL），and functional ambulation category scale（FAC）to evaluate walking function of the two groups. The resting⁃state functional magnetic resonance imaging（rs⁃fMRI）was performed，and Pearson test was used for correlation analysis. Results The BBS score，ASIA motor and sensory score and MBI score of the two groups after 2 and 4 weeks of intervention were higher than those before，and the changes were more obvious after 4 weeks of intervention（P < 0.05）；after 2 and 4 weeks of intervention，the numbers of patients with quadriceps muscle and hamstring muscle MMT and FAC of grade 3 or above ，and the number of patients with FAC of grade 3 or above increased in both groups，especially after 4 weeks of intervention（P < 0.05）；after 2 and 4 weeks of intervention，the above indexes of the study group changed significantly（P < 0.05）. After 4 weeks of intervention，the FC values between BA4L/BA41R and BA5L/BA48R in the study group were significantly higher than those before（P < 0.05），and were positively correlated with BBS score，ASIA motor and sensory score and MBI score（P < 0.05）. Conclusion BCI training on the basis of routine rehabilitation is helpful to improve motor function，sensory function and the quality of life of patients with spinal cord injury，and has a certain role in pro⁃ moting the improvement of balance and walking function.

Key words:

spinal cord injury, brain?computer interface training, lower limb motor function, walk? ing function