关键词:

高龄, 孕产妇, 妊娠结局, 孕早检, 孕检次数

Abstract:

Objective To explore the clinical characteristics and pregnancy outcomes in older parturient⁃ women，and study the influence of examination at first trimester and number of prenatal visits on pregnancy out⁃ comes among them. Methods A total of 108 734 parturient women from six urban districts of Nanning with both household registration and delivery registered in Nanning were recruited and allocated to the control group（aged 20 ~ 34 years）and the older group（aged ≥ 35 years）. The data of clinical characteristics and pregnancy outcomes were collected and retrospectively analyzed. Results The rate of the women who took the examination at first trimester andprenatal visits ≥ 5 times in the control group was significantly lower than that in the older group（P < 0.01）. The rates of those with the history of pregnancy ≥ 3 times，multiparity orcesarean section，spontaneous or induced abortion ≥ 3 times，assisted reproductive technology，multiple pregnancy，exposure to suspected teratogenic substances，or severe high⁃risk pregnancy in the older group were significantly higher than those of the control group （all P < 0.01）. The incidence rates of deliverywith < 37w gestation，lowbirth weight，extremely low birth weight， full ⁃term underweight，fetal growth restriction，macrosomia，Apgar scores below 7 at 5 min，cesarean section， birth defects and stillbirthin the oldergroup were significantly higher than those in the control（all P < 0.01）. Bymul⁃ tivariateLogistic regression，the examination at first trimester and prenatal visits ≥ 5 times were the protective factors of adverse pregnancy outcomes of elder parturient women such as delivery with < 37 w gestation，low birth weight，fetal growth restriction，Apgar scores below 7 at 5 min，cesarean section and stillbirth（all P < 0.05）. Conclusion Older parturient women are prone to adverse pregnancy outcomes，and fulfilled standard antenatal care may decrease the risk of adverse pregnancy outcomes among them.

Key words:

advanced age, parturient women, pregnancy outcomes, examination at first trimester, number of prenatal visits