实用医学杂志 ›› 2024, Vol. 40 ›› Issue (3): 432-438.doi: 10.3969/j.issn.1006-5725.2024.03.027

• 综述 • 上一篇    

食管鳞状上皮内瘤变的研究进展

高山,季坤,赵丽,邢妤佳,谢燕东,蔡习强()   

  1. 中国人民解放军第四军医大学第二附属医院消化内科 (西安 710038 )
  • 收稿日期:2023-08-16 出版日期:2024-02-10 发布日期:2024-02-22
  • 通讯作者: 蔡习强 E-mail:caixiqiang@163.com
  • 基金资助:
    军队保健专项科研课题(18BJZ10)

Research progress on esophageal squamous intraepithelial neoplasia

Shan GAO,Kun JI,Li ZHAO,Yujia XING,Yandong XIE,Xiqiang CAI()   

  1. Department of Gastroenterology,the Second Affiliated Hospital of the Fourth Military Medical University of PLA,Xi'an 710038,China
  • Received:2023-08-16 Online:2024-02-10 Published:2024-02-22
  • Contact: Xiqiang CAI E-mail:caixiqiang@163.com

摘要:

我国是食管癌高发国家,病理类型以鳞状细胞癌为主。鳞状上皮内瘤变是当前最为公认的食管鳞癌前病变,对其进行监测和干预是降低食管鳞癌发生率以及提高患者生活质量的有效方法。认识食管鳞状上皮内瘤变的病因、临床特征、诊断及治疗,对于食管鳞癌的预防和早期诊治发挥着至关重要的作用。目前食管鳞状上皮内瘤变相关临床研究仍不充分,临床处置也存在一定分歧。本综述在近年相关领域文献的基础上,从鳞状上皮内瘤变的危险因素、临床特征、诊断、转归及治疗方面进行总结综述,希望为食管鳞状上皮内瘤变临床管理提供思路。

关键词: 食管, 食管癌, 鳞状上皮内瘤变, 研究进展

Abstract:

China is a country with a high incidence of esophageal cancer. The pathological type is mainly squamous cell carcinoma. Squamous intraepithelial neoplasia is the most recognized precancerous lesion of esophageal squamous cell carcinoma, and its monitoring and intervention is an effective method to reduce the incidence of esophageal squamous cell carcinoma and improve the quality of life of patients. Understanding the etiology, clinical features, diagnosis and treatment of esophageal squamous cell carcinoma plays a crucial role in the prevention and early diagnosis and treatment of esophageal squamous cell carcinoma. At present, the clinical research related to esophageal squamous intraepithelial neoplasia is still insufficient, and there are some differences in clinical treatment. This review summarizes the risk factors, clinical features, diagnosis, prognosis and treatment of esophageal squamous intraepithelial neoplasia, hoping to provide ideas for the clinical management of esophageal squamous intraepithelial neoplasia.

Key words: esophagus, esophagus cancer, squamous intraepithelial neoplasia, Research progress

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