关键词: 阻塞性睡眠呼吸暂停与失眠共病,  , 单纯鼾症,  , 口腔矫治器,  , 多导睡眠图,  , 阻塞性 , 睡眠呼吸暂停,  , 睡眠

Abstract:

Objective This study aims to investigate the efficacy of mandibular advancement oral appliance（OA）for COMISA. Methods 14 patients with COMISA were selected as a comorbid group and 17 with primary snoring as a control group. All the patients were treated in the People′s Hospital of Guangxi Zhang Autonomous Region from April 2013 to August 2019. The polysomnography（PSG）parameters in the comorbid group before OA treatment and one month after treatment and those in the control group to treatment were compared. Results After OA treatment，sleep latency（SL），arousal index（ArI），apnea index（AI），apnea hypopnea index（AHI）decreased （P < 0.05），while total sleep time（TST），sleep efficiency（SE），N3 phase and lowest oxygen saturation（LSpO2） increased in the comorbid group（P < 0.05）. As compared with the control group，the percentage of SL，ArI，N1， TST，SE and N2 was larger in the comorbid group before treatment，but the percentage of TST，SE and N2 was smaller. After treatment，REM sleep latency and ArI were larger，and TST and SE were smaller in the comorbid group（P < 0.05）. Conclusions Oral appliance is a better therapy for COMISA.

Key words:

comorbid insomnia and sleep apnea, primary snoring, oral appliance, polysomnogra? phy, obstructive sleep apnea, sleep