The Journal of Practical Medicine ›› 2025, Vol. 41 ›› Issue (5): 766-772.doi: 10.3969/j.issn.1006-5725.2025.05.022

• Reviews • Previous Articles    

Research progress on role of anticoagulant drugs in prevention and treatment of cancer⁃associated venous thromboembolism

Xiaoli QIN1,Xiurong GAO2,Qin HE1,Zhumei LUO3,Qian. JIANG4()   

  1. *.Department of Pharmacy,the Third People's Hospital of Chengdu,Chengdu 610031,Sichuan,China
  • Received:2024-10-23 Online:2025-03-10 Published:2025-03-20
  • Contact: Qian. JIANG E-mail:jiangqian@scszlyy.org.cn

Abstract:

Cancer-associated venous thromboembolism (CAT) refers to the presence of venous thromboembolism including deep vein thrombosis and pulmonary embolism in patients with malignant cancer. Studies have indicated that CAT has become the second leading cause of death among cancer patients. Similar to other methods used to prevent and treat venous thromboembolism, anticoagulation remains to be the primary approach for CAT. However, the occurrence of CAT is influenced by various factors such as tumor type, staging, complications, treatment, and prognosis. This complexity makes the prevention and management of CAT more difficult and challenging. This article reviews the classification of commonly used anticoagulant drugs in clinical practice, emphasizing the current status and advancements in their application for the prevention and treatment of cancer-related venous thromboembolism in order to provide valuable reference for clinical medication.

Key words: cancer-associated venous thromboembolism, anticoagulant drugs, heparin, low molecular weight heparin, new anticoagulants

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