Abstract:

Objective To investigate the clinical effects and influencing factors of remote ischemic postconditioning RIPostC in the patients with post stroke fatigue （PSF）. Methods Eighty patients with PSF were randomly divided into experimental group（n = 40） and control group（n = 40）. Patients in both groups received routine drug therapy and rehabilitation training for stroke. The experimental group were additionally given RIPostC for four weeks. They were evaluated with National Institute of Health Stroke Scale（NIHSS）， Barthel Index（BI），Mini-mental State Examination（MMSE），fatigue severity scale（FSS）， Hamilton Anxiety Scale（HAMA）， and Hamilton Depression Scale（HAMD）. Results The score of NIHSS， FSS， HAMA and HAMD in the both groups were decreased， while the score of BI and MMSE were increased （P < 0.01）. The difference in the score of NIHSS， BI， MMSE， FSS， HAMA and HAMD between the two groups before and after treatment showed statistical significance （P < 0.01） and the difference in the score was more significant in the experimental group. The risk factors of FSS were MMSE and HAMA. Conclusion RIPostC can effectively improve the neurological deficits， daily activity ability and cognitive function， alleviate fatigue， anxiety and depression in the patients of PSF. The influencing factors of PSF are cognitive function and anxiety.

Key words: remote ischemic postconditioning, post stroke fatigue, cognitive function, anxiety