Abstract:

Traditional treatment for allergic diseases is primarily oral anti⁃allergy drugs，but long⁃term use has side effects，particularly in infants，pregnant women，and the elderly. According to research，the distribution and abundance of intestinal flora in patients with allergic diseases exhibit distinct characteristics，such as the bifold⁃ bacteroide inverted distribution phenomenon. Probiotics have been shown in studies to relieve allergic symptoms by regulating immune reactions，making them useful for the prevention and adjuvant treatment of allergic diseases. Probiotics significantly reduce the side effects of traditional anti ⁃ allergy drugs while being relatively inexpensive and having fewer side effects.Therefore，the general public readily accepts probiotics. As a result，probiotic anti⁃ allergic strain research and the development of related preparations have received a lot of attention.However，the mechanism by which probiotics treat allergic diseases is still unknown. Here，we review the progress of research into probiotics′ anti ⁃allergy mechanism，summarize clinical applications of probiotics，and finally forecast the future of probiotics for the prevention and treatment of allergic diseases.

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