收稿日期: 2023-08-18
网络出版日期: 2024-01-10
基金资助
江苏省第六期“333高层次人才培养工程”[编号:(2022)3-1-244)]
Risk factors of postoperative pulmonary complications in patients undergoing thoracic surgery in Day Care Unit
Received date: 2023-08-18
Online published: 2024-01-10
目的 探讨日间胸腔镜手术患者在出院后1个月内肺部并发症(PPCs)的发生率及其危险因素。 方法 选取2022年6-10月南京鼓楼医院集中式管理日间病房拟行择期电视辅助胸腔镜手术(VATS)患者200例,所有患者围术期实施加速康复外科(ERAS)管理。患者术后第1天晨由1名研究者在床旁行肺超声(LUS)检查。患者在出院后1月内至少在门诊完成1次X线或CT检查。根据影像学随访结果及患者复诊时临床症状主诉,明确是否发生PPCs,并将患者分为肺部并发症组(PPC+组)和正常组(PPC-组)。采用单因素分析VATS术后发生PPCs的相关影响因素,多因素logistic回归分析筛选独立危险因素。 结果 共有188例VATS患者接受了LUS检查并完成了1个月的随访,其中68例(36.1%)发生了不同种类的PPCs。多因素logistic回归分析显示,术前合并免疫系统疾病(OR = 24.36,95%CI:1.63 ~ 371.45,P = 0.021)、行肺叶切除术(OR = 1.01,95%CI:0.98 ~ 1.02,P = 0.031)和术后第1天LUSS高(OR = 1.37,95%CI:1.12 ~ 1.68,P = 0.002)是行日间VATS手术患者出院后1个月内发生PPCs的独立危险因素。 结论 合并免疫系统疾病、行肺叶切除术及术后第1天LUSS升高是日间VATS手术患者出院后1月内发生PPCs的独立危险因素。
路子蕴 , 孙行 , 徐璐 , 杨如松 , 王涛 , 史敏科 , 马正良 , 孙玉娥 , 李冰冰 . 日间胸腔镜手术患者术后肺部并发症危险因素分析[J]. 实用医学杂志, 2023 , 39(24) : 3205 -3209 . DOI: 10.3969/j.issn.1006-5725.2023.24.010
Objective To determine risk factors of postoperative pulmonary complications within 1 month in patients undergoing thoracic surgery in Day Care Unit. Methods The total of 200 patients routinely scheduled for VATS under centralized management were enrolled in this study. On the postoperative day 1, lung ultrasound (LUS) was conducted by one physician in the ward. The patients received at least once Chest X?ray or CT in outpatient department within 30 days after discharge. The composite of out?of?hospital PPCs, and the value of LUSS in predicting the PPCs was appraised. Furthermore, we identified the perioperative risk factors associated with PPCs in VATS patients. Results Of 200 recruited VATS patients eligible in the Nanjing Drum Tower Hospital, 188 participants received LUS examination and finally completed the 30 days follow?up. Of whom, 68 patients developed the varied types of PPCs. Multivariable Logistic regression analysis indicated that comorbidity of immune system disease(P = 0.021), lobar resection (P = 0.031) and the postoperative 24 hours LUSS (P = 0.002) were independent risk factors for PPCs within 30 days after VATS. Conclusion Comorbidity of immune system disease,lobar resection and the postoperative 24 h LUSS were independent risk factors for PPCs within 30 days after VATS。
| 1 | CAO C, LOUIE B E, MELFI F, et al. Outcomes of major complications after robotic anatomic pulmonary resection [J]. J Thorac Cardiovasc Surg, 2020, 159(2): 681-686. |
| 2 | XU X, CHEUNG D S T, SMITH R, et al. The effectiveness of pre- and post-operative rehabilitation for lung cancer: A systematic review and meta-analysis on postoperative pulmonary complications and length of hospital stay [J]. Clin Rehabil, 2022, 36(2): 172-189. |
| 3 | ZHENG Y, MAO M, LI F, et al. Effects of enhanced recovery after surgery plus pulmonary rehabilitation on complications after video-assisted lung cancer surgery: a multicentre randomised controlled trial [J]. Thorax, 2023, 78(6): 574-586. |
| 4 | 廖小清, 陈章, 戴维, 等. 肺癌术后并发症Clavien-Dindo分级≥Ⅱ级危险因素分析的多中心前瞻性队列研究 [J]. 中国胸心血管外科临床杂志, 2023, 30(8): 1151-1157. |
| 5 | MONASTESSE A, GIRARD F, MASSICOTTE N, et al. Lung Ultrasonography for the Assessment of Perioperative Atelectasis: A Pilot Feasibility Study [J]. Anesth Analg, 2017, 124(2): 494-504. |
| 6 | UHLIG C, NETO A S, VAN DER WOUDE M, et al. Intraoperative mechanical ventilation practice in thoracic surgery patients and its association with postoperative pulmonary complications: results of a multicenter prospective observational study [J]. BMC Anesthesiol, 2020, 20(1): 179. |
| 7 | COLQUHOUN D, LEIS A, SHANKS A, et al. A Lower Tidal Volume Regimen during One-lung Ventilation for Lung Resection Surgery Is Not Associated with Reduced Postoperative Pulmonary Complications [J]. Anesthesiology, 2021, 134(4): 562-576. |
| 8 | QUERO-VALENZUELA F, PIEDRA-FERNáNDEZ I, MARTíNEZ-CERES M, et al. Predictors for 30-day readmission after pulmonary resection for lung cancer [J]. J Surg Oncol, 2018, 117(6): 1239-1245. |
| 9 | 郭科迪, 武岩, 汤夕慧, 等. 术前衰弱对老年肺癌患者术后并发症的影响 [J]. 实用医学杂志, 2023, 39(15): 1956-1960. |
| 10 | ALTORKI N K, WANG X, WIGLE D, et al. Perioperative mortality and morbidity after sublobar versus lobar resection for early-stage non-small-cell lung cancer: post-hoc analysis of an international, randomised, phase 3 trial (CALGB/Alliance 140503) [J]. Lancet Respir Med, 2018, 6(12): 915-924. |
| 11 | SZABO M, BOZO A, DARVAS K, et al. The role of ultrasonographic lung aeration score in the prediction of postoperative pulmonary complications: an observational study [J]. BMC Anesthesiol, 2021, 21(1): 19. |
| 12 | 汪东升, 李晓红, 姜玉玉, 等. 术前肺超声评分与老年病人肺癌根治术术后肺部并发症的相关性研究 [J]. 蚌埠医学院学报, 2021, 46(5): 619-622. |
| 13 | ZIELESKIEWICZ L, PAPINKO M, LOPEZ A, et al. Lung Ultrasound Findings in the Postanesthesia Care Unit Are Associated With Outcome After Major Surgery: A Prospective Observational Study in a High-Risk Cohort [J]. Anesth Analg, 2021, 132(1): 172-181. |
/
| 〈 |
|
〉 |