实用医学杂志 ›› 2022, Vol. 38 ›› Issue (12): 1527-1532.doi: 10.3969/j.issn.1006⁃5725.2022.12.016

• 临床研究 • 上一篇    下一篇

准分子激光冠状动脉成形术在慢性完全闭塞高阻力病变介入治疗的有效性及安全性

张紫微1 杨俊1 王天杰2 唐炯1 郑甲林1 潘晓娟1 邹继宏1 齐峰1    

  1. 1 云南省阜外心血管病医院冠心病中心(昆明 650032);2 北京阜外心血管病医院(北京 100037)

  • 出版日期:2022-06-25 发布日期:2022-06-25
  • 通讯作者: 齐峰 E⁃mail:13987661111@qq.com
  • 基金资助:
    云南省心血管病临床医学中心项目(编号:FZX2019⁃06⁃01);云南省科技厅⁃昆明医科大学联合专项(编号:81170250)


Efficacy and safety of Excimer laser coronary angioplasty for the treatment of resistant chronic total occlu⁃ sion lesions

ZHANG Ziwei*,YANG Jun,WANG Tianjie,TANG Jiong,ZHENG Jialin,PAN Xiaojuan,ZOU Jihong, QI Feng.   

  1. Department of Center for Coronary Heart Disease,Fuwai Yunnan Cardiovascular Hospital,Kunming 650032,China

  • Online:2022-06-25 Published:2022-06-25
  • Contact: QI Feng E⁃mail:13987661111@qq.com

摘要:

目的 观察准分子激光冠状动脉成形术(excimer laser atherectomy,ELCA)在慢性完全闭塞 chronic total occlusion,CTO)高阻力病变中的应用的安全性和有效性。方法 总结自 2020 5 月至 2021 8 月在云南省阜外心血管病医院冠心病中心应用 CTO 导丝通过后球囊无法通过的病例共计 51 例,其中 22 例应用 ELCA,29 例采用其他临床常规方法,病例成功后均行血管内超声检查评估 CTO 段斑块性质并优化 PCI 治疗结果。手术成功定义为 ELCA 治疗后球囊及后续支架可通过病变,且支架植入后残余狭窄< 20%。结果 手术总成功率为 90.2%(46/51),ELCA 组成功率为 100%(22/22),非 ELCA 治疗组成功率为 82.7%(24/29),2组患者均未发生血管穿孔、心包填塞并发症。结论 应用ELCA 辅助CTO 高阻力病变PCI 治疗是安全有效的,可显著提高手术成功率。

关键词:

高阻力病变, 慢性闭塞, 准分子激光冠状动脉成形术, 经皮冠状动脉介入治疗

Abstract:

Objective To assess the efficacy and safety of Excimer laser coronary atherectomy(ELCA)in the treatment of resistant chronic total occlusion(CTO)lesions. Methods Fifty⁃one patients with severe resistant CTO lesions in Fuwai Yunnan Cardiovascular Hospital during May 2020 and August 2021 were included in the study,22 of them treated with ELCA and 29 with routine PCI. The plaque characters were analyzed and the final treatment effects were optimized by intravascular ultrasound(IVUS)after the successful procedures by which the balloons as well as the follow⁃up stents successfully went through the lesions and the residual stenosis was less than 20%. Results The total success rate of the two groups were 90.2%(46/51),that of the ELCA group reached 100% (22/22)and that of the non⁃ELCA group 82.7%(24/29). Neither coronary perforation nor acute cardiac tamponade occurred during the operation in both the groups. Conclusion ELCA is a valuable tool for the treatment of resistant CTO lesions. It helps to achieve optimal outcomes for the patients with severe resistant CTO lesions.

Key words:

resistant lesions, chronic total occlusion, excimer laser coronary angioplasty, percutat? neous coronary intervention