实用医学杂志 ›› 2022, Vol. 38 ›› Issue (14): 1715-1719.doi: 10.3969/j.issn.1006⁃5725.2022.14.001

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论糖尿病周围神经病变的诊治要点

金洁雯 李延兵   

  1. 中山大学附属第一医院内分泌科(广州510080)
  • 出版日期:2022-07-25 发布日期:2022-07-25
  • 通讯作者: 李延兵 E⁃mail:easd04lyb@126.com
  • 基金资助:
    科技部国家重点研发计划项目(编号:2018YFC1314100);广东省基础与应用基础研究基金项目(编号:2019A1515010275,
    2020A1515010049);广州市科技计划项目(编号:202002020053)

On the diagnosis and treatment of diabetic peripheral neuropathy

JIN Jiewen,LI Yanbing.   

  1. Department of En⁃ docrinology,the First Affiliated Hospital,Sun Yat⁃sen University,Guangzhou 510080,China 
  • Online:2022-07-25 Published:2022-07-25
  • Contact: LI Yanbing E⁃mail:easd04lyb@126.com

摘要:

糖尿病周围神经病变是糖尿病患者最常见的慢性并发症,是糖尿病足、骨折以及非创伤性截肢的重要危险因素,心血管自主神经病变同时也是糖尿病患者心血管事件以及心血管死亡的重要危险因素。但由于糖尿病周围神经病变早期往往无特异性症状,且半数以上患者早期无症状,待出现症状往往已是疾病晚期,严重影响患者生活质量及生命,但目前尚无有效治疗药物,被称为“沉默的杀手”。本文结合国内外最新指南共识,就糖尿病周围神经病变临床需重点关注的问题作一述评,以期提高临床对于糖尿病周围神经病变的关注度及早期防控。

关键词: 糖尿病周围神经病变, 早期诊断, 早期防控

Abstract:

Diabetic peripheral neuropathy is the most common chronic complication in diabetic patients and a major risk factor for diabetic foot,fracture,and non⁃traumatic amputation. Cardiovascular autonomic neuropathy is also a major risk factor for cardiovascular events and death in diabetics. Because diabetic peripheral neuropathy frequently has no specific symptoms at the early stage,and more than half of patients have no symptoms,it is frequently diagnosed at an advanced stage,which has a serious impact on patients′ quality of life and mortality.However,there is currently no effective treatment for diabetic peripheral neuropathy. As a result,diabetic peripheral neuropathy is also known as the“silent killer”. This article reviews the key clinical issues of diabetic peripheral neuropathy based on the most recent guidelines and consensus,with the goal of improving clinical attention and early prevention and control of diabetic peripheral neuropathy. 

Key words:

diabetic peripheral neuropathy, early diagnosis, early prevention and control

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