实用医学杂志 ›› 2022, Vol. 38 ›› Issue (13): 1662-1666.doi: 10.3969/j.issn.1006⁃5725.2022.13.018

• 临床研究 • 上一篇    下一篇

雾化熏蒸、睑板腺按摩对白内障合并睑板腺功能障碍患者术后干眼的疗效观察

程杰 于璐 郝晓琳 凌宇    

  1. 航天中心医院眼科(北京 100049)

  • 出版日期:2022-07-10 发布日期:2022-07-10
  • 通讯作者: 凌宇 E⁃mail:htyk721@126.com
  • 基金资助:
    航天科工集团 2020 年医疗卫生科研项目(临床医疗类)基金资助(编号:2020⁃LCYL⁃011)

Effectiveness of preoperative atomized fumigation and meibomian gland massage for dry eye after cataract operation in patients with meibomian gland dysfunction

CHENG Jie,YU Lu,HAO Xiaolin,LING Yu.   

  1. De⁃ partment Of Ophthalmology,Aerospace Central Hospital,Beijing 100049,China.

  • Online:2022-07-10 Published:2022-07-10
  • Contact: LING Yu E⁃mail:htyk721@126.com
  • Supported by:

摘要:

目的 探讨术前雾化熏蒸、睑板腺按摩对减缓睑板腺功能障碍(MGD)患者白内障术后干眼 的作用。方法 选取我院合并 MGD 的白内障患者 62 例,分为观察组 31 例(术前雾化熏蒸、睑板腺按摩、 抗炎治疗,术后常规抗炎治疗),对照组31例(术前术后常规抗炎治疗)。所有患者在术前和术后进行眼表 疾病指数 OSDI 问卷调查,泪膜脂质层厚度(LLT)、非接触泪液破裂时间(NIKBUT)、角膜荧光素染色 CFS)、睑缘、睑板腺分泌质量、睑板腺缺失的检查。结果 对照组患者MGD在术后1个月时病情加重,3 月后病情缓解。观察组术前治疗后,OSDI、NIKBUT、CFS、睑缘、睑板腺分泌质量评分、LLT 较治疗前均有 明显改善(P < 0.05);观察组 NIKBUT、睑缘、睑板腺分泌质量评分在术前治疗后、术后 1 周、术后 1 月及 术后 3 个月均显著高于对照组。观察组术后的睑缘充血及睑板腺口阻塞的情况较对照组同期明显改善 P < 0.05)。结论 白内障手术可加重 MGD 及干眼的症状,术前 MGD 的治疗对减轻白内障手术引起的干 眼是有效的。

关键词:

白内障, 干眼, 睑板腺功能障碍, 雾化熏蒸, 睑板腺按摩

Abstract:

Objective To investigate the effectiveness of preoperative atomized fumigation and meibomian gland massage on dry eye after cataract operation in patients with meibomian gland dysfunction(MGD). Methods A total of 62 cataract patients complicated with MGD in our hospital were selected and assigned to observation group(preoperative atomized fumigation,meibomian gland massage,anti⁃inflammatory treatment,routine anti⁃ inflammatory treatment after surgery=31)and control group(preoperative and postoperative routine anti⁃inflammatory treatment,= 31). All patients were inquired with Ocular Surface Disease Index(OSDI)questionnaire,tear lipid layer thickness LLT,noninvasive keratographic tear break⁃up time NIKBUT,corneal fluorescein staining(CFS), lidmargin,meibum quality and expressibility,and meibomian gland dropout before and after surgery. Results MGD in control group was aggravated 1 month after operation,and relieved 3 months later. In the observation group,OSDI,NIKBUT,CFS,blepharoplasty,meibomian gland secretion quality score and LLT were significantly improved after treatment(< 0.05). NIKBUT,blepharoplasty and meibomian gland secretion quality scores in the observation group were significantly higher than those in the control group after treatment,1 week,1 month and 3 months after surgery. Compared with the control group,the postoperative blepharoplasty hyperemia and meibomian gland orifice obstruction were significantly improved in the observation group(< 0.05). Conclusion MGD and dry eye were aggravated after cataract surgery,and preoperative treatment was effective in alleviating those symptoms.

Key words:

cataract, dry eye, meibomian gland dysfunction, atomized fumigation, meibomian gland massage