实用医学杂志 ›› 2022, Vol. 38 ›› Issue (12): 1548-1552.doi: 10.3969/j.issn.1006⁃5725.2022.12.019

• 临床护理 • 上一篇    下一篇

肿瘤重症患者发生亚谵妄综合征影响因素及护理方案的构建及应用

张进 肖正权 聂菁 饶竟 李文均    

  1. 重庆大学附属肿瘤医院重症医学科(重庆 400030)

  • 出版日期:2022-06-25 发布日期:2022-06-25
  • 通讯作者: 李文均 E⁃mail:fyteng444@126.com
  • 基金资助:
    重庆市科卫联合医学科研项目(编号:2020FYYX205)

Influencing factors and construction and application ofa nursing planfor sub⁃delirium syndrome in severe tumor patients

ZHANG Jin,XIAO Zhengquan,NIE Jing,RAO Jing,LI Wenjun.   

  1. Department of Intensive Care Affiliated Tumor Hospital of Chongqing University,Chongqing 400030,China

  • Online:2022-06-25 Published:2022-06-25
  • Contact: LI Wenjun E⁃mail:fyteng444@126.com ​

摘要:

目的 探讨肿瘤重症患者亚谵妄综合征发生的相关影响因素,并构建非药物治疗方案,分析其应用价值。方法 前瞻性纳入2020年9月至2021年3月我院收治的286例肿瘤重症患者为研究对象, 进行亚谵妄筛查,根据其是否发生亚谵妄将其分为亚谵妄组(SSD 组,n = 172)和非亚谵妄组(非 SSD 组, n = 114),收集患者的一般资料,通过单因素和多因素分析相关危险因素,并根据分析结果构建亚谵妄综 合征非药物治疗方案,通过随机数字表法将亚谵妄组患者分为常规方案干预组(对照组)和非药物治疗方 案干预组(研究组),各 86 例。比较两组患者谵妄发生率、干预后每日总睡眠时间、住院时间、睡眠质量得 分、认知功能得分、VAS 评分、HAMA 评分、APACHEⅡ评分及 PPI 评分差异,分析应用价值。结果 286 肿瘤重症患者的亚谵妄发生率为 60.13%,SSD 组患者 ECOG 评分、APACHEⅡ评分、PPI 评分较非 SSD 患者 偏高(P < 0.05)。阿片类药物、睡眠障碍、感染、PPI评分及APACHEⅡ评分均为肿瘤重症患者发生亚谵妄的 独立危险因素(P < 0.05)。 经非药物治疗方案干预后,研究组认知功能得分、睡眠质量得分及每日总睡眠 时间均明显高于对照组,住院时间较对照组更短(P < 0.05)。研究组 VAS 评分、HAMA 评分、APACHEⅡ 分及 PPI 评分均较对照组显著偏低(P < 0.05)。研究组谵妄发生率为 15.12%明显低于对照组 31.40%(P < 0.05)。结论 阿片类药物、睡眠障碍、感染、PPI 评分及 APACHEⅡ评分均是肿瘤重症患者亚谵妄综合征 的独立预测因子,根据风险分析结果构建的非药物治疗方案可显著改善患者的认知功能、睡眠质量、VAS 评分、PPI 评分及APACHEⅡ评分,缩短住院时间,降低亚谵妄发生率,临床应用价值较高。

关键词:

肿瘤重症, 亚谵妄综合征, 非药物治疗方案

Abstract:

Objective To explore the related influencing factors of sub⁃delirium syndrome in patients with severe tumor,and to construct a drug⁃free therapy and then to analyze its application value. Methods A total of 286 patients with severe tumor who were hospitalized from September 2020 to March 2021 were used as study subjects. They were screened for sub ⁃ delirium and divided into a sub ⁃ delirium group(SSD group,n = 172)and a group without sub⁃delirium(non⁃SSD,n = 114). The general data onthe patients were collected,and the univariate and multivariate analysis were applied to analyze the related risk factors. Based onthe analysis results,a drug ⁃free treatment plan for sub ⁃delirium syndrome was constructed. The sub ⁃delirium group weresubdivided into a routine plan intervention group(control group)and a drug⁃free treatment plan intervention group(study group)by using a random number table The incidence of delirium,total dailyhours ofsleep after intervention,hospital stay,sleep quality score,cognitive function score,VAS score,HAMA score,APACHEⅡscore and PPI score were compared between the two groups. The application value was analyzed. Results The rate of sub⁃delirium was 60.13% in 286 patients. The scores on ECOG,APACHEⅡ,and PPI were higher in the SSD group than in the non ⁃SSD group (P < 0.05). Opioids,sleep disorder,infection,PPI score and APACHEⅡscore were the independent risk factors for sub⁃delirium in patients with severe tumor(P < 0.05). After drug⁃freetreatment,thescores oncognitive function and sleep quality and the total daily hours ofsleep were significantly higherin the study groupthan inthe control group whilehospital stay was shorter(P < 0.05). Thescores on VAS,HAMA,APACHEⅡand PPI were significantly lower in the study group than in the control group(P < 0.05). The incidence rate of deliriumwas significantly lowerin the study group than in the control group(15.12% vs. 31.40%,P < 0.05). Conclusions Opioid drugs,sleep disorder,infection,PPI score and APACHE score are independent predictors of sub⁃delirium syndrome in patients with severe tumor. The drug⁃freetreatment protocol constructed based on the results of risk analysis can significantly improve cognitive function,sleep quality,VAS score,PPI score and APACHE score,shorten hospital stay,and reduce the incidence of sub⁃delirium. It shows higher clinical application value.

Key words:

severe tumor, sub?delirium syndrome, drug?free therapy plans