Objective To analyze the effect of preservation of partial urethral mucosa on urinary conti⁃ nence and sexual function in holmium laser enucleation of the prostate（HoLEP）. Methods From June 2018 to December 2021，the data of 73 patients with benign prostatic hyperplasia in our hospital were retrospectively analyzed. Among them，39 patients were treated with the modified HoLEP，and the others were treated with classic HoLEP. The two groups of patients were compared in terms of post⁃void residual volume（PVR），prostate specific antigen（PSA），peak urinary flow rate（Qmax），international prostate symptom score（IPSS），and quality of life （QOL）. The changes in urinary incontinence and sexual function（incidence of retrograde ejaculation and interna⁃ tional index of erectile function score）were observed in the two groups after operation. Results There was no significant difference in the amount of postoperative hemoglobin decline，the average operation time，indwelling catheterization time and weight of resected glands（P > 0.05）. After 12 months，there was no significant difference in PSA，Qmax，IPSS，QOL and IIEF⁃5 between the two groups（P > 0.05）. The incidence of transient urinary incontinence and retrograde ejaculation in the modified group was significantly better than that in the classic group （P < 0.05）. Conclusion The modified HoLEP with urethral mucosa preservation does not increase the risk of operation. With the same efficacy，it can effectively reduce the incidence of urinary incontinence and retrograde ejaculation，and improve the quality of life of patients after surgery