The Journal of Practical Medicine ›› 2026, Vol. 42 ›› Issue (7): 1126-1133.doi: 10.3969/j.issn.1006-5725.2026.07.002
• Guidelines·Consensus·Interpretation • Previous Articles
Received:2025-12-29
Revised:2025-01-14
Accepted:2025-01-16
Online:2026-04-10
Published:2026-04-13
CLC Number:
Tab.1
GRADE of recommendation and strength of evidence"
| 级别 | 详细说明 |
|---|---|
| 证据级别 | |
| 高质量(A) | 研究数据与真实效应值高度吻合,后续验证性研究难以动摇现有结论的可靠性 |
| 中等质量(B) | 现有研究提示效应值具备合理可信度,但存在一定误差可能。真实效应存在偏离当前估测值的潜在风险,补充研究可能对结论确定性产生显著影响 |
| 低质量(C) | 效应评估存在较大不确定性区间,真实效应与当前结论存在实质性差异的可能性较高。亟需更多研究验证,现有结论可能面临实质性修正 |
| 推荐强度 | |
| 强推荐(1) | 基于高质量证据的综合判断,干预措施在风险收益比、成本效益评估和患者预后改善方面具有显著优势。推荐意见适用于绝大多数临床情境 |
| 弱推荐(2) | 证据基础存在异质性或局限性,临床决策需权衡多方因素。可能涉及以下情况:疗效证据不确定、风险收益比存在争议、患者偏好差异显著,或需要结合具体医疗资源配置进行个体化决策 |
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