Abstract:

Objective To investigate the incidence and risk factors of low cardiac output syndrome （LCOS）after off⁃pump coronary artery bypass grafting（OPCABG）. Methods The clinical data of patients with OPCABG in the Department of Cardiovascular Surgery，Affiliated Hospital of Qingdao University from January 2018 to December 2020 were collected retrospectively. According to the diagnosis of aftersurgery，patients were divided into LCOS group and non ⁃LCOS group. The basic clinical characteristics of the two groups were recorder and compared，and the incidence of LCOS was calculated. Multivariate Logistic regression model was used to analyze the risk factors for LCOS after OPCABG. Results A total of 765 patients were included，LCOS group（n = 58） and non⁃LCOS group（n = 707）. The incidence of early LCOS after OPCABG was 7.58%. There were significant differences in preoperative arrhythmia，angina pectoris，restenosis after stent，cerebrovascular disease，pulmonary lesion，cervical vascular lesion，number of diseased branches，degree of left anterior descending artery disease， degree of right circumflex artery lesion，left ventricular ejection fraction（EF），left ventricular ejection fraction， left ventricular end ⁃diastolic diameter and intraoperative blood loss between the two groups. Multivariate Logistic regression analysis showed that preoperative cardiac arrhythmia（OR = 6.315，95%CI：1.404 ~ 28.396，P = 0.016）， angina pectoris（OR = 9.214，95%CI：2.153 ~ 39.424，P = 0.003），cerebral infarction（OR = 3.523，95%CI： 1.246 ~ 9.962，P = 0.018），pulmonary disease（OR = 5.505，95%CI：1.997 ~ 12.733，P = 0.001），carotid stenosis or occlusion（OR = 35.588，95%CI：11.874 ~ 106.662，P < 0.001）was an independent risk factor for postoperative LCOS in patients with OPCABG. Conclusion Preoperative arrhythmia，angina pectoris，cerebral infarction，pul⁃ monary lesion，carotid stenosis or occlusion were independent risk factors for LCOS after isolated OPCB.

Key words:

off?pump, coronary artery bypass grafting, low cardiac output syndrome