目的 探讨 C 反应蛋白与白蛋白比值（C⁃reactive protein/albumin Ratio，CAR）对支气管扩张 症急性加重的预测价值。方法 选取 107 例患者作为病例组，同期选取 97 例门诊健康体检者为对照组， 检测所有受试者血清中 C 反应蛋白（C⁃reactive protein，CRP）及白蛋白（albumin，ALB）的表达水平，并求得二者的比值 CAR。应用 Spearman 相关分析、有序 logistic 回归分析和 ROC 曲线分析探讨这三个指标与病情 程度的相关性及预测价值。结果 （1）病例组血清 CRP 水平明显高于对照组，病例组血清 ALB 水平明显 低于对照组，病例组CAR水平明显高于对照组（均P < 0.01）。（2）血清CRP和CAR与支气管扩张严重程度指 数（BSI）呈正相关，血清 ALB 与 BSI 呈负相关（均 P < 0.01）。（3）ALB 和 CAR 为支气管扩张症病情加重的风 险指标（均 P < 0.01）。CAR 受试者操作特征曲线下面积、敏感度和特异性均大于 ALB。结论 CAR 对重 度支气管扩张症具有较好的预测效能，建议将其作为其他评分系统的补充，有利于临床医生早期快速判 断患者病情程度从而制定最佳的治疗方案。

Objective To investigate the predictive value of C ⁃ reactive protein/albumin ratio（CAR）in acute exacerbation of bronchiectasis. Methods 107 patients were selected as the case group and 97 healthy outpatients were selected as the control group at the same time. The expression levels of C⁃reactive protein（CRP） and albumin（ALB）in serum of all subjects were detected，and the ratio（CAR）of CRP and ALB were calculated. Spearman correlation analysis，ordered Logistic regression analysis and ROC curve analysis were used to explore the correlation and predictive value between these three indicators and the degree of disease. Results （1）The serum CRP level in case group was significantly higher than that in control group，the serum ALB level in case group was significantly lower than that in control group，and the serum CAR level in case group was significantly higher than that in control group（all P < 0.01）.（2）Serum CRP and CAR were found to be positively correlated with BSI，while serum ALB was found to be negatively correlated with BSI（all P＜0.01）.（3）ALB and CAR were risk indicators for exacerbation of bronchiectasis（all P < 0.01）. CAR outperformed ALB in terms of area under the curve，sensitivity，and specificity. Conclusion CAR has good predictive efficacy for severe bronchiectasis，and it is suggested that CAR would be used as a supplement to other score systems，which is helpful for clinicians to quickly judge the severity of patients′ disease early and develop the best therapeutic regimen.