目的 对比观察 Oxford 单髁置换术（unicompartment knee replacement，UKR）与全膝关节置 换术（total knee arthroplasty，TKA）治疗内侧膝骨关节炎（knee osteoarthritis，KOA）的临床疗效。方法 采用回顾性研究的方式，收集 2015 年 6 月至 2019 年 6 月在广安门医院南区骨一科和东直门医院骨伤一 科行 UKR 或 TKA 的 100 例内侧 KOA 患者，按照手术方式分为单髁组 50 例和全膝组 50 例。比较 UKR 和 TKA 手术出血、手术时间和住院时间及术后 1 周、1 个月、3 个月、6 个月与 1 年后膝关节屈曲度、VAS 评 分、HSS 评分和并发症发生率。结果 UKR 手术出血量少于 TKA，UKR 手术时间以及住院时间短于 TKA（P < 0.05）；UKR 术后 1 周至 1 年膝关节屈曲度和 HSS 评分高于 TKA，UKR 术后 VAS 评分低于 TKA （P < 0.05）；UKR 临床疗效优良率术后 1 周至 6 月高于 TKA（P < 0.05），而术后 1 年的优良率差异无统计 学意义（P > 0.05）；UKR 和 TKA 术后相关并发症差异无统计学意义（P < 0.05）。结论 对于内侧 KOA 的患者 TKA 和 UKR 都是可行的治疗方案，术后一周至一年时间内 UKR 对于疼痛缓解及膝关节功能恢 复效果更佳。

Objective To compare the clinical efficacy of Oxford unicompartmentknee replacement （UKR）and total knee arthroplasty（TKA）in the treatment of medial knee osteoarthritis. Methods A total of 100 patients with medial knee osteoarthritis who underwent UKR and TKA from June 2015 to June 2019 in the first department of orthopedics and orthopedics，Dongzhimen Hospital from June 2015 to June 2019 were selected and divided into single condyle group and total knee group，with 50 cases in each group. Intraoperative blood loss，post⁃ operative total drainage volume，operation time and hospital stay，knee flexion，visual analogue scale（VAS）， American hospital for Special Surgery knee score（HSS）and the incidence of related complications were compared between the two groups. Results Less intraoperative blood loss and postoperative total drainage volume in single condyle group were found and the operation time and hospitalization time were shorter than those in the total knee group，indicating statistical significance（P < 0.05）. Knee flexion and HSS score of single condyle group were higher than those of the total knee group from 1 week to 1 year after operation，but VAS score was lower and the differ⁃ ence was statistically significant（P < 0.05）. The excellent rate of clinical effect in single condyle group from 1 week to 6 months after the operation was higher in single condyle group（P < 0.05）but no statistical difference wasfound 1 year after the operation（P > 0.05）. There was no significant difference in the incidence of postoperative complications between the two groups（P < 0.05）. Conclusion TKA and UKR are feasible treatment for medial knee osteoarthritis. UKR has a better effect on pain relief and knee function recovery within 1 week to 1 year after operation.