1 首都医科大学附属北京胸科医院,北京市结核病胸部肿瘤研究所耐药结核病研究北京市重点实验室细 菌免疫室(北京101149);2 安徽医科大学生命科学学院遗传学教研室(合肥230032);3 安徽医科大学第二 附属医院肿瘤科(合肥230601)
网络出版日期: 2021-08-25
基金资助
Advances of long non⁃coding RNA MALAT1 in diagnosis and treatment of tumors
Online published: 2021-08-25
李悄, 李国政, 张博, 王伟
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长链非编码RNA MALAT1在肿瘤诊治中的研究进展
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Long non⁃coding RNA(lncRNA)is a kind of non⁃coding transcripts longer than 200nt. Abnormal expression of lncRNAs is associated with various types of tumors. MALAT1,one of the first lncRNAs to be discov⁃ ered,can regulate the proliferation,apoptosis,metastasis and invasion of tumor cells through different pathways and affect the progression of tumors. The present study reviews the current status of MALAT1 in many kinds of tumors,and provides a novel perspective on the diagnosis and treatment of tumors.
Key words:
MALAT1
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