目的 通过 meta 分析了解我国脑卒中后抑郁患者（PSD）患病情况。方法 检索知网、万方、 维普、PubMed 等数据库，收集 2021 年 2 月 28 日前有关中国脑卒中后抑郁患病率相关研究文献。利用 Stata 11.0 软件进行 meta 分析。结果 共纳入 50 篇文献，总样本量 22 822 例。meta 分析结果显示中国 PSD 总患 病率为 34.9%（95%CI：31.7% ~ 38.1%）。亚组分析显示女性患病率高于男性、复发患者患病率高于首发患 者，差异均有统计学意义（P < 0.05）。不同婚姻状态、受教育程度、年龄、地区、调查年份、卒中类型和卒中部位之间差异没有统计学意义。结论 我国卒中后抑郁患者患病率较高，应及早识别卒中后抑郁患者， 并进行科学治疗及干预

Objective To understand the prevalence of post⁃stroke depression in China by using a meta⁃ analysis. Methods After searching the databases including CNKI，Wangfang，VIP，and Pubmed，we collected the relevant literature on the prevalence of post ⁃ stroke depression in China before February 28，2021. The Stata 11.0 software was used for meta⁃analysis. Results A total of 50 articles were included，with a total sample size of 22 822 persons. The prevalence of post⁃stroke depression in China was 34.9%（95%CI：3.17% ~ 38.1%）. A sub⁃ group analysis showed that the prevalence of female was higher than that of male，and the prevalence of recurrent patients was higher than that of incipient patients，the differences were statistically significant（P < 0.05）. There were no significant differences in marital status，education level，age，residential region，survey year，stroke types and stroke location. Conclusions The prevalence of post ⁃ stroke depression is higher in China. Clinicians should identify patients with post⁃stroke depression as early as possible，and carry out proper treatment and inter⁃ vention.