Risk factors of cervical lymph nodule metastasis on papillary thyroid carcinoma based on C⁃TIRADS
Department of Ultrasound,the First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China
Online published: 2021-06-25
目的 2020 年 8 月我国学者发布了符合中国国情的甲状腺影像报告和数据系统(Chinese Thyroid Imaging Reporting and Data System,C⁃TIRADS),由于该系统发布时间不久,它的应用尚未普及。现本研究利用 C⁃TIRADS 分析甲状腺乳头状癌(papillary thyroid carcinoma,PTC)出现颈部淋巴结转移(cervical lymph nodule metastasis,CLNM)的风险因素,为临床诊断和治疗提供依据。方法 回顾性分析本院194例术后 病理诊断为PTC的结节,根据PTC是否出现颈部淋巴结转移分为转移组和非转移组,对PTC的C⁃TIRADS 评分和颈部淋巴结转移之间的关系进行单因素及多因素 logistic 回归分析。结果 转移组患者 C⁃TIRADS 评 分为 4.0(2.0,5.0),高于非转移组患者(P < 0.01)。经多因素 logistic 回归分析提示,PTC 的患者性别(OR = 0.288,95%CI:0.12 ~ 0.689,P = 0.005)、年龄(OR = 0.964,95%CI:0.936 ~ 0.992,P = 0.011)和 PTC 的大 小(OR = 4.506,95%CI:2.275 ~ 8.922,P < 0.01)、数量(OR = 3.502,95%CI:1.681 ~ 7.296,P = 0.001)及 C⁃TIRADS 评分(OR = 1.948,95%CI:1.227 ~ 3.091,P = 0.005)是 PTC 出现颈部淋巴结转移的独立危险因 素。结论 PTC 的 C⁃TIRADS 评分联合结节数量和大小及患者的性别、年龄对预测其是否出现颈部淋巴结转移具有重要意义。
关键词:
甲状腺乳头状癌
刘承开 张蕾 王晓东
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基于C-TIRADS淋巴结转移的影响因素分析甲状腺乳头状癌出现颈部
Objective To study the risk factors of cervical lymph nodule metastasis(CLNM)on papillary thyroid carcinoma(PTC)based on Chinese thyroid imaging report and data system(C⁃TIRADS). Methods A total of 194 patients diagnosed as PTC by surgery and pathological indication were included in the research. All selected participants were divided into lymph nodule metastasis group and lymph nodule negative group respectively accord⁃ ing to the presence of CLNM. Then,the relationship between C⁃TIRADS score of PTC and CLNM was analyzed by univariate and multivariate logistic regression analysis. Results The score of C ⁃TIRADS was 4.0(2.0,and 5.0) among the patients with CLNM,higher than those without cervical lymph nodule metastasis(P < 0.01). Multivariate logistic regression analysis indicated that sex(OR = 0.288,95%CI:0.12~0.689,P = 0.005),age(OR = 0.964, 95%CI:0.936~0.992,P = 0.011),size(OR = 4.506,95%CI:2.275~8.922,P < 0.01)and number(OR = 3.502,95% CI:1.681~7.296,P = 0.001)of the nodule and C ⁃ TIRADS score(OR = 1.948,95% CI:1.227~ 3.091,P = 0.005)were risk factors for CLNM. Conclusion C ⁃ TIRADS score of PTC combined with patients′ sex,age and size and number of the nodule is of great significance in predicting CLNM of PTC.
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