酒精性肝病（alcohol liver disease，ALD）是由于长期大量饮酒导致的肝脏疾病，初期表现为脂肪肝，可发展为肝纤维化、肝硬化，甚至肝癌。近年来，代谢组学在ALD中的研究取得了一定进展，已应用于生物标志物和发病机制的研究。本文就代谢组学在ALD中的研究进展进行综述，以期为其防治提供参考。

Alcoholic liver disease is one type of liver disorders caused by chronic heavy alcoholic drinking. It appears as fatty liver in the early stage，and then may develop fibrosis，cirrhosis，or even liver cancer. Recent⁃ ly，research on metabolomics for ALD has achieved some progress，applying to the studies on biomarkers and pathogenesis of ALD. In this paper，the research progress of metabolomics in ALD was reviewed to aim at providing reference for the prevention and treatment of it.