目的 探讨超声引导下多靶点精准注射联合展肩悬蹲锻炼法治疗原发性冻结肩的临床疗效，并分析对体内炎性因子的影响。 方法 将2022年5月至2025年2月期间于遵义市中医院收治的冻结肩患者120例随机分为治疗组（n = 60）和对照组（n = 60）。对照组行超声引导下多靶点精准注射，治疗组在对照组基础上联合展肩悬蹲锻炼法治疗，比较两组治疗前后疼痛程度、肩关节功能评分、肩关节被动活动度、炎症水平、治疗有效率及安全性。 结果 两组经干预后的视觉模拟量表（visual analog scale， VAS）评分、炎症因子C 反应蛋白（C-reactive protein，CRP）、白细胞介素-6（interleukin-6，IL-6）、肿瘤坏死因子-α（tumor necrosis factor-α，TNF-α）均有降低，且治疗组的VAS评分和炎症水平（CRP、IL-6、TNF-α）明显低于同期对照组（P < 0.05）。两组经干预后Constant-Murley肩功能、前屈、后伸及外旋活动范围评分均有提升，且同期的治疗组明显高于对照组（P < 0.05）；治疗组的总有效率明显高于同期的对照组（P < 0.05），2组患者均未发生严重不良反应。 结论 与单纯超声引导下多靶点精准注射相比，联合展肩悬蹲锻炼法治疗原发性冻结肩临床效果更佳，可促进肩关节功能的恢复，减轻炎症反应，为临床治疗冻结肩的方案选择提供参考。

Objective To investigate the clinical efficacy of ultrasound-guided multi-target precise injection combined with the shoulder suspension squat exercise method in treating primary adhesive capsulitis of the shoulder， and to analyze its effects on inflammatory factors. Methods A total of 120 patients in Zunyi Municipal Hospital of Traditional Chinese Medicine with adhesive capsulitis were randomly divided into a treatment group （60 cases） and a control group （60 cases）. The control group underwent ultrasound-guided multi-target precise injections， while the treatment group received the same injections combined with the shoulder suspension squat exercise method. Compared the scores of pain and shoulder joint function， passive range of motion， inflammatory levels， treatment efficacy， and safety before and after treatment. Results After intervention， both groups showed reduced （Visual analog scale， VAS） scores and inflammatory levels （C-reactive protein，CRP）， （interleukin-6，IL-6）， （tumor necrosis factor-α，TNF-α）， and the treatment group exhibited significantly lower VAS scores and inflammatory levels compared to the control group （P < 0.05）. Both groups demonstrated improved Constant-Murley shoulder function scores， forward flexion， backward extension， and external rotation range of motion scores after intervention， and the treatment group significantly higher than the control group （P < 0.05）. The overall effective rate of the treatment group was significantly higher than the control group （P < 0.05）. None of the patients experienced serious adverse reactions. Conclusions Compared to ultrasound-guided multi-target precise injections， the combined shoulder suspension squat exercise had superior clinical efficacy in treating primary frozen shoulder. It promoted shoulder joint function recovery， reduced inflammation， and provided a valuable reference for selecting clinical treatment options for frozen shoulder.