收稿日期: 2026-01-06
网络出版日期: 2026-04-29
基金资助
河北省政府资助临床医学优秀人才培养项目(ZF2025161);中央引导地方科技发展资金项目(自由探索类基础研究)(246Z7742G);第二师铁门关市财政科技计划项目(2025GG3104);中央引导地方科技发展资金项目(区域科技创新体系项目)(246Z7702G)
Effects of photobiomodulation on the stellate ganglion region on postoperative sleep quality and pain in breast cancer patients
Received date: 2026-01-06
Online published: 2026-04-29
目的 探讨星状神经节区光生物调节对乳腺癌患者术后睡眠及疼痛的干预效果。 方法 选取2024年6—12月于保定市第一中心医院择期行全身麻醉下乳腺癌改良根治术的患者114例,年龄18 ~ 65岁,ASA Ⅰ—Ⅲ级,体质量指数18 ~ 30 kg/m2。采用随机数字表法将患者分为对照组(C组)和干预组(T组)。C组患者除常规麻醉操作外,不进行任何干预;T组患者在全身麻醉后接受单次星状神经节区线偏振光照射。照射参数设定为功率80%,照射/间歇周期为2 s/4 s,总时长为40 min。记录两组患者术前1 d(D0)、术后第2天(D2)及术后第5天(D5)的匹兹堡睡眠质量指数(PSQI)评分、总睡眠时间、睡眠效率及夜间觉醒次数,并比较D2时的视觉模拟评分和术后48 h内患者自控镇痛有效按压次数及术后不良事件的发生和患者满意度。 结果 与C组相比,T组患者在D2、D5时的PSQI评分及术后睡眠障碍发生率明显降低(P < 0.001);在睡眠客观指标方面,T组患者的总睡眠时间与睡眠效率均显著增加(P < 0.001),而夜间觉醒次数显著减少(P < 0.001)。与C组相比,T组在D2的视觉模拟评分显著降低,有效按压次数明显减少(P < 0.001);T组恶心呕吐发生率显著降低(P < 0.001),患者满意度评分显著升高(P < 0.001)。 结论 星状神经节区光生物调节能有效改善乳腺癌术后患者的睡眠质量,降低术后睡眠障碍发生率,同时有助于减轻术后疼痛,提升患者满意度,且安全性良好。
刘伟明 , 王曼 , 王泽广 , 袁栋欣 , 孙菲 , 邵娟 , 张秀宁 , 霍修林 , 于沛霞 , 张末 , 郄晓娟 . 星状神经节区光生物调节对乳腺癌患者术后睡眠及疼痛的干预效果[J]. 实用医学杂志, 2026 , 42(9) : 1511 -1516 . DOI: 10.3969/j.issn.1006-5725.2026.09.004
Objective To investigate the effects of photobiomodulation on the stellate ganglion region in patients undergoing breast cancer surgery, specifically on their postoperative sleep disturbance and pain. Methods A total of 114 patients who were scheduled to undergo modified radical mastectomy for breast cancer under general anesthesia at Baoding First Central Hospital from June 2024 to December 2024 were selected. The participants were aged between 18 and 65 years, with an ASA physical status of Ⅰ - Ⅲ and a body-mass index ranging from 18 - 30 kg/m2. By using a random number table, the patients were randomly allocated into either the control group (Group C) or the intervention group (Group T). Patients in Group C did not receive any intervention, whereas those in Group T underwent linearly polarized light irradiation over the stellate ganglion region after general anesthesia. The irradiation parameters were set as follows: A power setting of 80%, an irradiation/intermittent cycle of 2 seconds/4 seconds, and a total duration of 40 minutes. Data were recorded for both groups on the day before surgery (D0), postoperative day 2 (D2), and postoperative day 5 (D5), including the Pittsburgh Sleep Quality Index (PSQI) score, total sleep time (TST), sleep efficiency (SE), and the number of nocturnal awakenings (NA). Additionally, the Visual Analog Scale (VAS) scores on D2, the number of effective patient-controlled analgesia (PCA) presses within 48 hours after surgery, the incidence of postoperative adverse events, and patient satisfaction were compared between the two groups. Results Patients in the T group showed significantly lower PSQI scores and a lower incidence of post-operative sleep disorder (PSD) on the D2 and D5 compared to those in Group C (P < 0.001). In comparison with Group C, the T group had significantly longer TST and higher SE on D2 and D5 (P < 0.001), as well as a significantly reduced NA (P < 0.001). When compared to Group C, the T group presented a significantly lower VAS score and a notable reduction in the total number of PCA compressions on D2 (all P < 0.001). Moreover, the incidence of nausea and vomiting was significantly lower in the T group than in Group C (P < 0.001), whereas patient satisfaction scores were significantly higher (P < 0.001). Conclusion Photobiomodulation applied to the stellate ganglion region can reduce the incidence of PSD, improve sleep quality, alleviate pain, and enhance patient satisfaction in breast cancer patients, while maintaining a favorable safety profile.
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