常氧条件下，糖酵解增强是许多肿瘤的重要特征之一，此过程被称为有氧糖酵解或瓦博格 （Warburg）效应，是病毒复制和生存的必要条件，因此病毒感染极有可能增强糖酵解过程。肿瘤病毒在潜 伏感染过程中会诱导有氧糖酵解和乳酸产生，提示病毒诱导的糖酵解可能在肿瘤相关进展中起关键作 用。病毒及病毒编码的相关蛋白通过调节葡萄糖的吸收和乳酸的代谢、增加糖酵解酶的活性及调节葡萄 糖代谢信号，从而影响糖酵解过程。本文概述了病毒感染与糖酵解的相关性，并具体阐述了病毒感染所 导致糖酵解过程的改变，以期从糖酵解途径寻找抗病毒治疗新靶点。

Under normoxic conditions，enhanced glycolysis is one of the important characteristics of many tumors. This process is called aerobic glycolysis or Warburg effect，which is a necessary condition for virus replica⁃ tion and survival. Therefore，viral infection is very likely to enhance glycolysis Solution process. Tumor viruses induce aerobic glycolysis and lactic acid production during latent infection，suggesting that virus⁃induced glycolysis may play a key role in tumor ⁃ related progression. Viruses and virus ⁃encoded related proteins affect the glycolysis process by regulating glucose absorption and lactic acid metabolism，increasing glycolytic enzyme activity and regulating glucose metabolism signals. This article outlines the correlation between viral infections and glycolysis， and specifically explains the changes in glycolysis caused by viral infections，with a view to finding new targets for antiviral therapy from glycolysis pathways.