目的 探讨阴性淋巴结切除数量对卵巢癌患者总生存期和复发率的影响。 方法 回顾性选取2021年10月至2023年10月运城市中心医院收治的150例卵巢癌患者作为研究对象。按照阴性淋巴结切除数量标准三分位数分为T1组（≤ 17枚）、T2组（18 ~ 27枚）、T3组（≥ 28枚）。收集临床特征、手术指标，分析复发与生存情况。 结果 临床特征分析结果显示，3组患者在年龄、绝经状态、体质量指数（body mass index，BMI）、Charlson合并症指数（charlson comorbidity index，CCI）、家族肿瘤史等临床特征方面均差异无统计学意义（P > 0.05）。3组患者在手术方式、残余病灶大小、术后并发症上比较差异无统计学意义（P > 0.05），手术时间方面T1组< T2组<T3组（P < 0.05），T3组出血量多于T1组（P < 0.05）。3组整体上复发率比较差异无统计学意义（P > 0.05），但随着淋巴结切除数量的增加（从T1组到T3组）复发率呈现出统计学上显著的下降趋势（P < 0.05）。Cox回归分析显示：单变量分析表明每增加一个阴性淋巴结，死亡风险降低4.7%（HR = 0.953，P < 0.05）；多变量分析（调整混杂因素后）显示风险降低5.8%（HR = 0.942，P < 0.05）。限制性立方样条（RCS）分析证实两者呈显著线性关联（P < 0.05），以5个淋巴结为参考，切除10、20、30个的风险比分别为1.003、0.760和0.317，趋势显示随淋巴结数量增加，死亡风险持续下降。多因素Cox分析显示，T3组较T1组死亡风险降低68%（P < 0.05），FIGO Ⅲ期风险增加3.11倍（P < 0.05），高级别肿瘤风险增加2.80倍（P < 0.05）。 结论 卵巢癌患者阴性淋巴结切除数量与预后呈线性相关，切除淋巴结数量越多，患者死亡风险越低，充分的淋巴结切除应作为卵巢癌手术治疗的重要组成部分。

Objective To explore the impact of the number of negative lymph node resections on the overall survival and recurrence rate of patients with ovarian cancer. Methods A retrospective selection was made of 150 ovarian cancer patients admitted to our hospital from October 2021 to October 2023 as the research subjects. According to the standard of the number of negative lymph nodes removed， they were divided into three groups： T1 group （≤ 17）， T2 group （18 ~ 27）， and T3 group （≥ 28）. Clinical characteristics and surgical indicators were collected， and the recurrence and survival situations were analyzed. Results The clinical characteristic analysis results showed that there were no statistically significant differences among the three groups in terms of age， menopausal status， BMI， CCI， family history of tumors， etc. （P > 0.05）. There were no significant differences in surgical methods， residual lesion size， postoperative complications among the three groups （P > 0.05）. In terms of operation time， T1 group < T2 group < T3 group （P < 0.05）， and the bleeding volume in T3 group was more than that in T1 group （P < 0.05）. There was no significant difference in the overall recurrence rate among the three groups （P > 0.05）， but with the increase in the number of lymph node resections （from T1 group to T3 group）， the recurrence rate showed a statistically significant downward trend （P < 0.05）. Cox regression analysis showed that the univariate analysis indicated that for each additional negative lymph node， the risk of death decreased by 4.7% （HR = 0.953， P < 0.05）； the multivariate analysis （after adjusting for confounding factors） showed that the risk decreased by 5.8% （HR = 0.942， P < 0.05）. Restricted cubic spline （RCS） analysis confirmed a significant linear association between the two （P < 0.05）. With 5 lymph nodes as the reference， the risk ratios for 10， 20， and 30 resections were 1.003， 0.760， and 0.317， respectively， and the trend showed that the risk of death continued to decrease as the number of lymph nodes increased. Multivariate Cox analysis showed that the risk of death in T3 group was 68% lower than that in T1 group （P < 0.05）， the risk in FIGO stage Ⅲ was 3.11 times higher （P < 0.05）， and the risk in high-grade tumors was 2.80 times higher （P < 0.05）. Conclusions The number of negative lymph nodes removed in patients with ovarian cancer is linearly correlated with prognosis. The more lymph nodes removed， the lower the risk of death for the patients. Adequate lymph node removal should be an important part of the surgical treatment for ovarian cancer.