指南解读

欧洲麻醉与重症医学会《成人非心脏手术的术中血流动力学监测和管理声明》的解读

  • 徐婉卓 ,
  • 薄禄龙
展开
  • 中国人民解放军海军军医大学第一附属医院麻醉学部 (上海 200433 )

收稿日期: 2025-07-14

  网络出版日期: 2025-11-13

Interpretation of the statement from the European Society of Anaesthesiology and Intensive Care: Intra-operative hemodynamic monitoring and management of adults having noncardiac surgery

  • Wanzhuo XU ,
  • Lulong. BO
Expand
  • Faculty of Anesthesiology,the First Affiliated Hospital of Naval Medical University,Shanghai 200433,Shanghai,China

Received date: 2025-07-14

  Online published: 2025-11-13

摘要

术中血流动力学监测与管理是成人非心脏手术围术期管理的核心环节,对保障组织灌注、预防器官损伤具有重要意义。2025年6月,欧洲麻醉与重症医学会发布《成人非心脏手术的术中血流动力学监测和管理声明》,该声明由25位国际多学科专家基于循证医学证据制定,涵盖动脉血压管理、心率调控、每搏输出量与心输出量监测、心脏前负荷评估及液体反应性判断、微循环监测、麻醉深度与脑氧饱和度监测等六大方面。本文对声明要点进行解读,包括监测方法的选择与局限性、各项指标的管理策略(如推荐以平均动脉压≥ 60 mmHg为管理基准,不建议将动脉压作为心输出量的替代指标等),旨在为国内麻醉医师提供临床参考,优化成人非心脏手术患者的术中血流动力学管理。

本文引用格式

徐婉卓 , 薄禄龙 . 欧洲麻醉与重症医学会《成人非心脏手术的术中血流动力学监测和管理声明》的解读[J]. 实用医学杂志, 2025 , 41(21) : 3305 -3310 . DOI: 10.3969/j.issn.1006-5725.2025.21.001

Abstract

Intraoperative hemodynamic monitoring and management are essential components of perioperative care for adult patients undergoing non?cardiac surgery, as they are critical for maintaining adequate tissue perfusion and preventing organ dysfunction. In June 2025, the European Society of Anaesthesiology and Intensive Care (ESAIC) published the “Statement on Intraoperative Hemodynamic Monitoring and Management in Adult Non? Cardiac Surgery.” Developed by a panel of 25 international multidisciplinary experts using an evidence?based approach, this statement addresses six key domains: arterial blood pressure management, heart rate regulation, stroke volume and cardiac output monitoring, assessment of cardiac preload and fluid responsiveness, application of microcirculation monitoring techniques, and integrated management of anesthesia depth with cerebral oxygen saturation monitoring. This article provides a comprehensive interpretation of the statement′s core recommendations, including guidance on the selection and limitations of monitoring modalities, as well as specific management targets for instance, recommending a mean arterial pressure of at least 60 mmHg as a threshold for intervention and explicitly advising against the use of arterial pressure as a surrogate for cardiac output. The objective is to offer practical clinical guidance for anesthesiologists and to enhance the precision and effectiveness of intraoperative hemodynamic management in adult non?cardiac surgical patients.

参考文献

[1] SAUGEL B, BUHRE W, CHEW M S, et al. Intra-operative haemodynamic monitoring and management of adults having noncardiac surgery: A statement from the European Society of Anaesthesiology and Intensive Care[J]. Eur J Anaesthesiol, 2025, 42(6): 543-556. doi:10.1097/eja.0000000000002174
[2] HASEGAWA D, SATO R, DUGGAL A, et al. Comparison of central and peripheral arterial blood pressure gradients in critically ill patients: A systematic review and meta-analysis[J]. Crit Care Explor, 2024, 6(6): e1096. doi:10.1097/cce.0000000000001096
[3] SCHUMANN R, MEIDERT A S, BONNEY I, et al. Intraoperative blood pressure monitoring in obese patients[J]. Anesthesiology, 2021, 134(2): 179-188. doi:10.1097/aln.0000000000003636
[4] ISHIGAMI J, CHARLESTON J, MILLER E R J 3rd, et al. Effects of cuff size on the accuracy of blood pressure readings: The Cuff(SZ) randomized crossover trial[J]. JAMA Intern Med, 2023, 183(10): 1061-1068. doi:10.1001/jamainternmed.2023.3264
[5] MEIDERT A S, DOLCH M E, MUHLBAUER K, et al. Oscillometric versus invasive blood pressure measurement in patients with shock: A prospective observational study in the emergency department[J]. J Clin Monit Comput, 2021, 35(2): 387-393. doi:10.1007/s10877-020-00482-2
[6] THOMPSON A, FLEISCHMANN K E, SMILOWITZ N R, et al. 2024 AHA/ACC/ACS/ASNC/HRS/SCA/SCCT/SCMR/SVM Guideline for Perioperative Cardiovascular Management for Noncardiac Surgery: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines[J]. J Am Coll Cardiol, 2024, 84(19): 1869-1969.
[7] SAUGEL B, KOUZ K, MEIDERT A S, et al. How to measure blood pressure using an arterial catheter: A systematic 5-step approach[J]. Crit Care, 2020, 24(1): 172. doi:10.1186/s13054-020-02859-w
[8] KOUZ K, WEGGE M, FLICK M, et al. Continuous intra-arterial versus intermittent oscillometric arterial pressure monitoring and hypotension during induction of anaesthesia: The AWAKE randomised trial[J]. Br J Anaesth, 2022, 129(4): 478-486. doi:10.1016/j.bja.2022.06.027
[9] NAYLOR A J, SESSLER D I, MAHESHWARI K, et al. Arterial catheters for early detection and treatment of hypotension during major noncardiac surgery: A randomized trial[J]. Anesth Analg, 2020, 131(5): 1540-1550. doi:10.1213/ane.0000000000004370
[10] MUKKAMALA R, STERGIOU G S, AVOLIO A P. Cuffless blood pressure measurement[J]. Annu Rev Biomed Eng, 2022, 24: 203-230. doi:10.1146/annurev-bioeng-110220-014644
[11] KOUZ K, WEIDEMANN F, NAEBIAN A, et al. Continuous finger-cuff versus intermittent oscillometric arterial pressure monitoring and hypotension during induction of anesthesia and noncardiac surgery: The DETECT randomized trial[J]. Anesthesiology, 2023, 139(3): 298-308. doi:10.1097/aln.0000000000004629
[12] WESSELINK E M, WAGEMAKERS S H, VAN WAES J A R, et al. Associations between intraoperative hypotension, duration of surgery and postoperative myocardial injury after noncardiac surgery: A retrospective single-centre cohort study[J]. Br J Anaesth, 2022, 129(4): 487-496. doi:10.1016/j.bja.2022.06.034
[13] SAUGEL B, ANNECKE T, BEIN B, et al. Intraoperative haemodynamic monitoring and management of adults having noncardiac surgery: Guidelines of the German Society of Anaesthesiology and Intensive Care Medicine in collaboration with the German Association of the Scientific Medical Societies[J]. J Clin Monit Comput, 2024, 38(5): 945-959. doi:10.1007/s10877-024-01132-7
[14] SAUGEL B, FLETCHER N, GAN T J, et al. PeriOperative Quality Initiative (POQI) international consensus statement on perioperative arterial pressure management[J]. Br J Anaesth, 2024, 133(2): 264-276. doi:10.1016/j.bja.2024.04.046
[15] KOUZ K, BROCKMANN L, TIMMERMANN L M, et al. Endotypes of intraoperative hypotension during major abdominal surgery: A retrospective machine learning analysis of an observational cohort study[J]. Br J Anaesth, 2023, 130(3): 253-261. doi:10.1016/j.bja.2022.07.056
[16] SHIMADA T, MASCHA E J, YANG D, et al. Intra-operative hypertension and myocardial injury and/or mortality and acute kidney injury after noncardiac surgery: A retrospective cohort analysis[J]. Eur J Anaesthesiol, 2022, 39(4): 315-323. doi:10.1097/eja.0000000000001656
[17] KLEIN A A, MEEK T, ALLCOCK E, et al. Recommendations for standards of monitoring during anaesthesia and recovery 2021: Guideline from the Association of Anaesthetists[J]. Anaesthesia, 2021, 76(9): 1212-1223. doi:10.1111/anae.15501
[18] KOUZ K, HOPPE P, REESE P, et al. Relationship between intraoperative and preoperative ambulatory nighttime heart rates: A secondary analysis of a prospective observational study[J]. Anesth Analg, 2021, 133(2): 406-412. doi:10.1213/ane.0000000000005625
[19] KOUZ K, BERGOLZ A, TIMMERMANN L M, et al. The relation between mean arterial pressure and cardiac index in major abdominal surgery patients: A prospective observational cohort study[J]. Anesth Analg, 2022, 134(2): 322-329. doi:10.1213/ane.0000000000005805
[20] SAUGEL B, THIELE R H, HAPFELMEIER A, et al. Technological assessment and objective evaluation of minimally invasive and noninvasive cardiac output monitoring systems[J]. Anesthesiology, 2020, 133(4): 921-928. doi:10.1097/aln.0000000000003483
[21] BOOTSMA I T, BOERMA E C, SCHEEREN T W L, et al. The contemporary pulmonary artery catheter Part 2: Measurements, limitations, and clinical applications[J]. J Clin Monit Comput, 2022, 36(1): 17-31. doi:10.1007/s10877-021-00673-5
[22] MILLER T E, MYTHEN M, SHAW A D, et al. Association between perioperative fluid management and patient outcomes: A multicentre retrospective study[J]. Br J Anaesth, 2021, 126(3): 720-729. doi:10.1016/j.bja.2020.10.031
[23] PEREL A. Using dynamic variables to guide perioperative fluid management[J]. Anesthesiology, 2020, 133(4): 929-935. doi:10.1097/aln.0000000000003408
[24] MESSINA A, CAPORALE M, CALABRO L, et al. Reliability of pulse pressure and stroke volume variation in assessing fluid responsiveness in the operating room: A metanalysis and a metaregression[J]. Crit Care, 2023, 27(1): 431. doi:10.1186/s13054-023-04706-0
[25] VINCENT J L, CECCONI M, DE BACKER D. The fluid challenge[J]. Crit Care, 2020, 24(1): 703. doi:10.1186/s13054-020-03443-y
[26] MALBRAIN M, LANGER T, ANNANE D, et al. Intravenous fluid therapy in the perioperative and critical care setting: Executive summary of the International Fluid Academy (IFA)[J]. Ann Intensive Care, 2020, 10(1): 64. doi:10.1186/s13613-020-00679-3
[27] OSTERMANN M, AUZINGER G, GROCOTT M, et al. Perioperative fluid management: Evidence-based consensus recommendations from the international multidisciplinary PeriOperative Quality Initiative[J]. Br J Anaesth, 2024, 133(6): 1263-1275. doi:10.1016/j.bja.2024.07.038
[28] TRAUZEDDEL R F, ERTMER M, NORDINE M, et al. Perioperative echocardiography-guided hemodynamic therapy in high-risk patients: A practical expert approach of hemodynamically focused echocardiography[J]. J Clin Monit Comput, 2021, 35(2): 229-243. doi:10.1007/s10877-020-00534-7
[29] FLICK M, HILTY M P, DURANTEAU J, et al. The microcirculation in perioperative medicine: A narrative review[J]. Br J Anaesth, 2024, 132(1): 25-34. doi:10.1016/j.bja.2023.10.033
[30] FLICK M, SCHREIBER T H, MONTOMOLLI J, et al. Microcirculatory tissue perfusion during general anaesthesia and noncardiac surgery: An observational study using incident dark field imaging with automated video analysis[J]. Eur J Anaesthesiol, 2022, 39(7): 582-590. doi:10.1097/eja.0000000000001699
[31] 《成人非心脏手术围术期血压监测与管理指南》撰写组,中国老年医学学会医疗照护分会. 成人非心脏手术围术期血压评估与管理指南[J]. 中华保健医学杂志,2023,25(2):121-128.
文章导航

/