目的 探索肝硬化腹水患者高动力循环相关指标（HR、E/A和LVDF）的影响因素。 方法 回顾性分析昆明市第三人民医院2022年10月至2024年10月诊断为肝硬化腹水的377例患者的临床资料，根据腹水分级分为1级、2级与3级腹水组，比较3组患者的一般资料与临床指标，通过Spearman相关性分析、非参数检验等单因素分析筛选阳性指标，采用二元logistic回归和多重线性回归探索影响肝硬化腹水患者高动力循环相关指标（HR、E/A和LVDF）的影响因素。 结果 不同腹水组在HR、E/A和LVDF发生率上存在差异（P < 0.05）。年龄、腹水深度、血清Cl^-、CO₂、RDW-CV以及病因为肝硬化腹水患者HR的独立影响因素，年龄、WBC、ALB和病毒导致的肝硬化为影响肝硬化腹水患者E/A的独立影响因素，年龄（OR = 1.088，95%CI：1.062 ~ 1.114，P < 0.001）、K⁺（OR = 1.919，95%CI：1.218 ~ 3.025， P = 0.005）是肝硬化腹水患者LVDF的独立危险因素，RDW-CV（OR = 0.902，95%CI：0.883 ~ 0.961， P = 0.023）与ALB（OR = 0.921，95%CI：0.883 ~ 0.961， P < 0.001）是保护因素。 结论 对于肝硬化腹水患者高动力循环相关指标，血清 ALB 是E/A和LVDF、血清K⁺和 RDW-CV 是 LVDF、血清 CL^-是心率的独立影响因素。临床上需要加强对这些指标的监测及干预。

Objective To investigate the factors influencing hyperdynamic circulation-related indicators in patients with liver cirrhosis and ascites. Methods A retrospective analysis was conducted on the clinical data of 377 patients diagnosed with cirrhosis-associated ascites at the Third People's Hospital of Kunming between October 2022 and October 2024. Patients were categorized into grade 1， grade 2， and grade 3 ascites groups according to ascites severity grading. The general demographic characteristics and clinical parameters of the three groups were compared. Potential positive predictors were initially identified through univariate analyses， including Spearman correlation and non-parametric tests. Binary logistic regression and multiple linear regression models were subsequently employed to investigate the factors influencing high dynamic circulation-related indicators （heart rate ［HR］， E/A ratio， and left ventricular diastolic function ［LVDF］） in patients with cirrhosis-related ascites. Results Significant differences in the incidence of HR， the ratio of early to late diastolic filling velocities （E/A）， and LVDF were observed among different ascites groups （P < 0.05）. Age， ascites depth， serum chloride （Cl^-）， CO₂， red cell distribution width coefficient of variation （RDW-CV）， and etiology were identified as independent determinants of HR in patients with liver cirrhosis and ascites. Age， white blood cell count （WBC）， albumin （ALB）， and etiology were independent determinants of E/A in patients with liver cirrhosis and ascites. Age （OR = 1.088， 95%CI 1.062–1.114， P < 0.001） and serum potassium （K⁺） （OR = 1.919， 95%CI 1.218–3.025， P = 0.005） were independent risk factors for LVDF in patients with cirrhotic ascites， whereas RDW-CV （OR = 0.902， 95%CI 0.883–0.961， P = 0.023） and ALB （OR = 0.921， 95%CI 0.883–0.961， P < 0.001） were identified as protective factors. Conclusions Serum ALB is an independent influencing factor for E/A ratio and LVDF in cirrhotic patients with ascites and hyperdynamic circulation. K⁺ and RDW-CV are also independent predictors of LVDF， whereas Cl^- independently influences heart rate. Clinical monitoring and targeted intervention for these parameters should be emphasized.