临床新进展

常见结核后肺疾病的诊疗进展

  • 刘晓宁 ,
  • 梁雅雪 ,
  • 王华
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  • 安徽省胸科医院结核病学科 (安徽 合肥 230022 )
王华,主任医师,现任安徽省胸科医院耐药结核科主任,结核大学科主任。安徽省临床重点专科学术带头人,安徽省医学会结核病学分会主任委员,安徽省结核病专业质控中心主任,中国防痨协会第十二届理事会理事,中华医学会结核病分会NTM专委会副主任委员,中国防痨协会临床试验专业分会常委委员,中国防痨协会结核病临床专业分会常委委员,安徽省医师协会结核病学分会副主任委员,《中华结核和呼吸杂志》通讯编委。擅长耐药结核病、糖尿病合并结核、结核性脓胸、淋巴结结核、骨关节结核、结核性脑膜炎等疑难危重症结核和非结核分枝杆菌病的临床诊治。主持省卫健委科研课题2项,荣获安徽省科技进步二等奖一项,发表中文核心期刊论文及SCI论文30余篇。参与国家级和省级科研课题30余项,主编科普书籍1本,参编行业团标、指南、专家共识及科普书籍18部。

收稿日期: 2025-06-06

  网络出版日期: 2025-10-10

基金资助

安徽省卫生健康科研项目(AHWJ2022b040)

The current status and diagnostic and therapeutic progress of common post⁃tuberculosis pulmonary disease

  • Xiaoning LIU ,
  • Yaxue LIANG ,
  • Hua. WANG
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  • Anhui Chest Hospital,Hefei 230022,Anhui,China

Received date: 2025-06-06

  Online published: 2025-10-10

摘要

结核病目前仍是全球最大的单一传染性病原体致死原因,我国目前仍是结核病高负担国家之一,结核后肺疾病(post-tuberculosis pulmonary disease, PTLD)造成的肺组织结构和功能损伤给人们造成的疾病负担不容小觑;但因既往人们对结核后肺疾病的认知不足,导致结核后人群缺乏该疾病的长程管理。本文对常见的PTLD的流行病学及危害、发病机制、临床表现、诊断方法、治疗和预防措施等方面进行阐述,以期结核科医师强化对PTLD的认识和重视,并对PTLD在病因机制、诊疗方法等存在的局限性以及亟需深入研究的紧迫性加以概述。

本文引用格式

刘晓宁 , 梁雅雪 , 王华 . 常见结核后肺疾病的诊疗进展[J]. 实用医学杂志, 2025 , 41(19) : 2985 -2990 . DOI: 10.3969/j.issn.1006-5725.2025.19.005

Abstract

Tuberculosis remains the leading cause of death from a single infectious agent worldwide. China is still one of the countries with a high burden of tuberculosis. The structural and functional damage to lung tissue caused by post-tuberculosis pulmonary disease (PTLD) imposes a considerable disease burden on people. However, due to the insufficient understanding of post-tuberculosis lung diseases in the past, the long-term management of this disease has been lacking for the post-tuberculosis population. This article elaborates on the epidemiology and hazards, pathogenesis, clinical manifestations, diagnostic methods, treatment and preventive measures of common PTLD, with the aim of enhancing the awareness and attention of tuberculosis physicians to PTLD. It also summarizes the limitations in the etiological mechanism, diagnosis and treatment methods of PTLD, as well as the urgency of in-depth research.

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