收稿日期: 2025-05-15
网络出版日期: 2025-08-11
基金资助
国家自然青年科学基金项目(822015453);湖南省中医药科研计划一般项目(D2022030);湖南中医药大学校院联合基金一般项目(2024XYLH245)
The effect of “Tongdu Tiaoshen” acupuncture combined with hand function training in treatment of hand dysfunction after cerebral infarction
Received date: 2025-05-15
Online published: 2025-08-11
目的 探讨“通督调神”针刺法联合手功能康复训练治疗脑梗死后患者手功能障碍的临床疗效。 方法 将104例患者随机分为两组,每组52例。观察组行“通督调神”针刺联合手功能康复训练)。对照组行手功能康复训练,治疗4周。观察患者治疗前后的改良Ashworth评分(MAS)、改良Lindmark评分(MLS)、Brunnstrom上肢运动功能评分(BMS)、Fugl-Meyer上肢运动功能评分(FMA)、改良Barthel指数(MBI)、握力值(GS)等观察指标变化,记录不良事件发生情况,统计各组有效率,进行疗效对比。 结果 在除掉剔除病例和脱落病例后有94例纳入最终统计,观察组有48例,对照组有46例。两组患者的MLS、MAS、BMS、FMA、MBI、GS等指标分值较治疗前均有明显变化(P < 0.05);治疗后两组进行组间比较发现各项指标的分值差异均有统计学意义(P < 0.05);观察组总有效率为91.7%,对照组为82.6%,两组的疗效等级差异有统计学意义(P < 0.05)。 结论 “通督调神”针刺法联合手功能训练在改善脑梗死后患者的手功能障碍情况,提高患肢的手部握力和精细动作能力,降低手部肌肉痉挛、关节僵硬程度,以及促进上肢运动功能恢复和改善患者日常生活能力等方面均要明显优于手功能康复训练的治疗。
朱拓 , 赵怡灯 , 詹海兰 , 周权 . “通督调神”针刺联合手功能训练治疗脑梗死后手功能障碍[J]. 实用医学杂志, 2025 , 41(15) : 2418 -2425 . DOI: 10.3969/j.issn.1006-5725.2025.15.019
Objective To evaluate the clinical efficacy of "Tongdu Tiaoshen" acupuncture combined with hand function rehabilitation training in patients with hand dysfunction following cerebral infarction. Methods A total of 104 patients were randomly assigned to either the observation group (receiving "Tongdu Tiaoshen" acupuncture combined with hand function rehabilitation training) or the control group (undergoing hand function rehabilitation training alone), with 52 patients in each group. Both groups underwent a 4-week treatment regimen. The following outcome measures were assessed pre- and post-treatment: Modified Ashworth Scale (MAS), Modified Lindmark Scale (MLS), Brunnstrom Motor Function Score (BMS) for upper limbs, Fugl-Meyer Assessment (FMA) of upper limb motor function, Modified Barthel Index (MBI), and grip strength (GS). Adverse events were documented, and the clinical efficacy in each group was evaluated by calculating the effective rate. Results After excluding dropouts, a total of 94 cases were included in the final statistical analysis, with 48 cases assigned to the observation group and 46 to the control group. Both groups demonstrated significant improvements in MLS, MAS, BMS, FMA, MBI, and GS scores compared to pre-treatment levels, with all differences being statistically significant (P < 0.05). Following treatment, intergroup comparisons also revealed statistically significant differences in all measured indicators (P < 0.05). The total effective rate was higher in the observation group (91.7%) than in the control group (82.6%), and the difference in efficacy grades between the two groups was statistically significant (P < 0.05). Conclusions "Tongdu Tiaoshen" acupuncture, when combined with hand function training, demonstrates significantly greater efficacy than hand function rehabilitation training alone in improving post-cerebral infarction hand dysfunction. It enhances grip strength and fine motor coordination of the affected limb, alleviates hand muscle spasticity and joint stiffness, and promotes recovery of upper limb motor function, thereby improving patients' activities of daily living. This integrated therapeutic approach warrants further clinical validation and in-depth research for broader implementation.
| [1] | 谢秋蓉,林婉琪,张琪,等. 脑卒中上肢康复智能化评估和虚拟现实训练研究进展[J]. 康复学报, 2023, 33(3): 271-279. |
| [2] | 王陇德. 《中国卒中中心报告2022》概要[J]. 中国脑血管病杂志, 2024, 21(8): 565-576. |
| [3] | 郭飞,黄云慧,黄宇靖,等. 醒脑静注射液联合阿替普酶治疗缺血性脑卒中疗效和安全性的系统评价[J]. 实用医学杂志, 2022, 38(2): 206-211. doi:10.3969/j.issn.1006?5725.2022.02.015 |
| [4] | 骆凝,李化,李新锋,等. 早日康复治疗对老年脑梗死的疗效[J]. 中国老年学杂志, 2024, 44(24): 6119-6122. |
| [5] | 张君宇,韩为,金子开,等. “通督调神”针法结合康复训练对缺血性脑卒中后下肢运动功能恢复的影响[J]. 康复学报, 2022, 32(5): 401-406, 418. |
| [6] | 孙培养,吴立斌,李佩芳,等. 通督调神针刺治疗脑卒中后平衡功能障碍临床研究[J]. 针灸临床杂志, 2020, 36(7): 12-15. |
| [7] | 徐志新,韩为,张利达,等. 通督调神针刺法对高同型半胱氨酸血症患者颈动脉内-中膜厚度及脑血流动力学的影响[J]. 山西中医药大学学报, 2021, 22(6): 426-430. |
| [8] | 孙青,赵见文,王峰,等. 化浊解毒活血通络方联合通督调神针刺法治疗急性脑梗死疗效及NLRP3信号通路研究[J]. 中国中医急症, 2024, 33(7): 1200-1204. |
| [9] | 孙培养,李佩芳,王涛,等. “通督调神”针刺对脑卒中后抑郁大鼠海马PI3K/Akt/mTOR通路及自噬相关蛋白的影响[J]. 中国针灸, 2020, 40(11): 1205-1210. |
| [10] | 高玉宝,吴伟伟,朋源凤,等. 通督调神针刺法联合胞磷胆碱对脑梗死后血管性痴呆患者认知功能、血液流变学和脑血流动力学的影响[J]. 现代生物医学进展, 2022, 22(17): 3347-3350, 3392. |
| [11] | 孙培养,蔡荣林,李佩芳,等. “通督调神”针刺对脑卒中后抑郁大鼠海马神经元保护作用及单胺类神经递质的影响[J]. 中国针灸, 2019, 39(7): 741-747. |
| [12] | 朱继民. 医学统计分析方法[M]. 合肥:中国科学技术大学出版社, 2016. |
| [13] | 陈伟. 关刺经筋结点结合康复训练治疗中风后手功能障碍的临床疗效观察[D]. 哈尔滨:黑龙江中医药大学, 2023. |
| [14] | 中华人民共和国国家卫生健康委员会,中华人民共和国国家卫生健康委员会. 脑血管病防治指南(2024年版)[J]. 磁共振成像, 2025, 16(1): 1-8. |
| [15] | 《辽宁中医药大学学报》编辑部. 中风的诊断依据、证候分类、疗效评定——中华人民共和国中医药行业标准《中医内科病证诊断疗效标准》(ZY/T001.1-94)[J]. 辽宁中医药大学学报, 2016, 18(10): 16. |
| [16] | 程珂,沈雪勇. 经络腧穴学习题集(供中医学针灸推拿学康复治疗学等专业用第3版全国中医药行业高等教育十四五规划教材) 大中专理科医药卫生[M]. 北京:中国中医药出版社, 2022. |
| [17] | 赖丽萍,谭家航,赖丽萍,等. PNF技术对脑卒中偏瘫患者手功能康复的重要性探讨[J]. 中医临床研究, 2019, 11(13): 141-142. |
| [18] | 林志杰. 张力平衡电针治疗脑卒中后偏瘫患者手功能障碍的临床疗效观察[D]. 福州:福建中医药大学, 2022. |
| [19] | LAN C, HUANG Z Q, LUO X X, et al. The Correlations Between Serum Hcy Level and Seizures and Cognitive Function in Patients After Stroke[J]. Am J Alzheimer's Dis Other Dement, 2022, 37: 15333175221146738. doi:10.1177/15333175221146738 |
| [20] | VIDMAR T, KREGAR N G, Puh U. Reliability of the Modified Ashworth Scale After Stroke for 13 Muscle Groups[J]. Arch Phys Med Rehabil, 2023, 104(10): 1606-1611. doi:10.1016/j.apmr.2023.04.008 |
| [21] | UCHIYAMA Y, DOMEN K, KOYAMA T. Brain regions associated with Brunnstrom and functional independence measure scores in patients after a stroke: A tract-based spatial statistics study[J]. J Phys Ther Sci, 2023, 35(3): 211-216. doi:10.1589/jpts.35.211 |
| [22] | AKTER R, SHARMA N, AHMED S, et al. Combined effect of Brunnstrom's hand rehabilitation and functional electrical stimulation for improving hand function in patients with chronic stroke: A randomized controlled trial[J]. J Bodywork Move Ther, 2023, 35: 84-90. doi:10.1016/j.jbmt.2023.04.021 |
| [23] | KARIN W, ANNE S, LOUISA M, et al. Interrater reliability of the Fugl-Meyer Motor assessment in stroke patients: A quality management project within the ESTREL study[J]. Front Neurol, 2024, 15: 1335375. doi:10.3389/fneur.2024.1335375 |
| [24] | SOFIA F, ANTONIOS G, ISMENE-A D, et al. Reliability and validity of the Greek adaptation of the Modified Barthel Index in neurorehabilitation patients[J]. Eur J Phys Rehabil Med, 2024, 60(1): 44-54. doi:10.23736/s1973-9087.23.08056-5 |
| [25] | 霍瑞霞. 早期运动疗法对脑卒中偏瘫患者肢体功能康复效果的影响[J]. 中国实用护理杂志, 2011, 27(21): 2. |
| [26] | 曹蓉,伊文超,甘兆丹,等. 便携电子测力仪测量握力和捏力的信度与效度[J]. 江苏医药, 2022, 48(11): 1153-1155, 1159. |
| [27] | HASAN-ATACAN T, OZGUN-KAYA K, SEDEF S. Correlation of hand functionality and grip strengths with anthropometric measurements[J]. Work, 2021, 69(1): 187-195. doi:10.3233/wor-213468 |
| [28] | 魏家军,魏家军. 脑梗死的中西医治疗进展[J]. 天津药学, 2016, 28(4): 56-58. |
| [29] | 刘霖,朱琳,单桂香,等. 卒中偏瘫患者手功能康复治疗的研究进展[J]. 中国脑血管病杂志, 2018, 15(9): 500-505. |
| [30] | 刘四维,关敏,高强,等. 任务导向性训练在脑卒中后偏瘫康复中的应用进展[J]. 中国康复医学杂志, 2020, 35(3): 374-378. |
| [31] | PROULX C E, HIGGINS J, GAGNON D H. Occupational therapists’ evaluation of the perceived usability and utility of wearable soft robotic exoskeleton gloves for hand function rehabilitation following a stroke[J]. Disabi Rehabil Assist Technol, 2023, 18(6): 953-962. doi:10.1080/17483107.2021.1938710 |
| [32] | SU J Q, WANG J X, WANG W Q, et al. An Adaptive Hybrid Brain–Computer Interface for Hand Function Rehabilitation of Stroke Patients[J]. IEEE Trans Neural Syst Rehabil Eng, 2024, 32: 2950-2960. doi:10.1109/tnsre.2024.3431025 |
| [33] | 苏诚欢,苏诚欢. 针灸结合Rood疗法治疗脑卒中后上肢功能障碍的疗效观察[J]. 广州中医药大学学报, 2016, 33(1): 35-38. |
| [34] | 韩为,张道宗. 张道宗通督调神学术思想的临床应用[J]. 中医药临床杂志, 2012, 24(3): 225-228. |
| [35] | 李章晗,黎华茂,艾年年. 通督调神针刺法联合康复运动治疗脑卒中恢复期偏瘫肢体运动功能障碍的临床观察[J]. 广州中医药大学学报, 2021, 38(7): 1401-1406. |
| [36] | 王婧吉,李难,徐明安,等. 通督调神针刺法对血管性非痴呆型认知功能障碍患者事件相关电位P300的影响[J]. 辽宁中医药大学学报, 2016, 18(1): 149-151. |
| [37] | 高希言,陈岩,孙婵娟,等. 李鼎教授对奇经八脉的认识[J]. 中国针灸, 2011, 31(7): 653-656. |
| [38] | 张雪萍,张佳乐,计辰洋,等. “泛督脉”视域下的脏腑疾病诊治思路及临床应用探讨[J]. 北京中医药大学学报, 2023, 46(1): 100-105. |
| [39] | 胥林波,胥林波. 督脉与脊髓的关系探析[J]. 现代中西医结合杂志, 2011, 20(30): 3844-3845. |
| [40] | 张倩,周美启,张倩,等. 奇经八脉的经脉脏腑相关研究[J]. 中国针灸, 2017, 37(12): 1299-1302. |
| [41] | 王鸿波,张弘,陈伊,等. 通督调神针法对脑梗死恢复期椎-基底动脉血流影响的临床研究[J]. 针灸临床杂志, 2018, 34(8): 24-27. |
| [42] | 王琪,李澎,许军峰,等. 针刺水沟穴治疗缺血性脑损伤机制研究进展[J]. 针灸临床杂志, 2021, 37(7): 88-91. |
| [43] | 张震,何腾,王旭,等. 基于“督脉入络脑”探讨针刺督脉经穴治疗脑病的神经传导机制[J]. 山东中医杂志, 2024, 43(8): 795-803. |
| [44] | 杨珊,王恺,刘念,等. 督脉针刺合舌三针联合康复训练对老年脑卒中失语症患者语言功能、认知水平及炎症因子的影响[J]. 中国老年学杂志, 2023, 43(19): 4630-4633. |
| [45] | 陈静影,刘赤,罗凌飞,等. 脑血管再生修复的细胞基础和分子调控机制[J]. 中国科学:生命科学, 2022, 52(5): 618-632. |
/
| 〈 |
|
〉 |