目的 基于面部年轻化和鼻唇沟皱纹的改善，评估聚对二氧环己酮（PPDO）双向锯齿线倒V型布线法与直线型布线法用于改善鼻唇沟皱纹的临床疗效分析。 方法 选取2023年3月至2024年1月，60例因鼻唇沟皱纹至蚌埠医科大学第一附属医院整形外科行PPDO皮下埋植提升术的求美者，随机分为观察组和对照组，根据其面部松垂特点和程度设计埋线数量和分布，观察组予以倒V型布线提升，对照组予以传统的直线型布线提升。分别于术后4、12、24周随访并统计临床疗效、面部整体改善情况、记录并发症评估手术安全性以及满意度调查。 结果 术后两组患者各个时间段的皱纹严重程度评定量表（WSRS）评分较术前均有所下降，差异具有统计学意义（P < 0.05）；两组患者术后各对应时间点的WSRS均为观察组低于对照组，差异具有统计学意义（P < 0.05）；两组患者均为术后12周时WSRS评分最低，术后24周评分虽较术后12周有所增加，差异具有统计学意义（P < 0.05）；观察组面部整体改善的有效率为93.33%，明显高于对照组的73.33%，差异有统计学意义（χ² = 4.320，P <0.05）；两组均无明显并发症发生；观察组患者满意度为4.067 ± 0.828，显著高于对照组3.400 ± 0.932，差异有统计学意义（t = 2.929，P < 0.05）。 结论 PPDO双向锯齿线倒V型布线法与直线型布线法均能较好地改善鼻唇沟皱纹；倒V型布线法相较于直线型布线法的提升效果更显著，受试者满意度高，耗材更少；两种布线方式均在术后第12周达到最佳效果；两种手术方式均无明显并发症发生。

Objective To assess the clinical effectiveness of Poly（p-dioxanone）（PPDO） bidirectional sawtooth inverted V-shaped wiring and straight wiring in ameliorating nasolabial fold wrinkles within the context of facial rejuvenation. Methods Between March 2023 and January 2024， 60 patients presenting with nasolabial fold wrinkles who underwent PPDO subcutaneous implantation and lifting in the Department of Plastic Surgery at the First Affiliated Hospital of Bengbu Medical University were randomly allocated into an observation group and a control group. At 4 weeks， 12 weeks， and 24 weeks post-surgery， the clinical efficacy was statistically analyzed. The incidence of complications was documented to evaluate the safety of the procedure， and a satisfaction survey was carried out. Results In each time period， the Wrinkle Severity Rating Scale （WSRS） scores of both groups decreased significantly when compared to those prior to the operation （P < 0.05）. At each corresponding time point after surgery， there was a statistically significant difference in the WSRS scores between the two groups in the observation group （P < 0.05）. In both groups， the WSRS score was the lowest at 12 weeks post-surgery， and the score at 24 weeks post-surgery was significantly higher than that at 12 weeks post-surgery （P < 0.05）. The overall effective rate of facial improvement in the observation group was 93.33%， which was significantly higher than that in the control group （73.33%）. The difference was statistically significant （χ² = 4.320， P < 0.05）. No obvious complications occurred in either group. The satisfaction rate in the observation group was 4.067 ± 0.828， which was significantly higher than that in the control group （3.400 ± 0.932）. The difference was statistically significant （t = 2.929， P < 0.05）. Conclusions Both the PPDO two-way sawtooth line inverted V-shaped wiring method and the straight wiring method can effectively improve nasolabial fold wrinkles. Compared with the straight wiring method， the inverted V wiring method demonstrates a more pronounced improvement effect， higher subject satisfaction， and fewer consumables. The optimal results were achieved at 12 weeks after surgery for both wiring methods. Moreover， neither surgical procedure was associated with significant complications.