医学检查与临床诊断

三维斑点追踪成像技术联合左室压力-应变环对冠心病早期患者左心室收缩功能减退的评估价值

  • 叶白冰 ,
  • 李秀娟 ,
  • 陈赛君
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  • 1.宁波大学医学部 (浙江 宁波 315211 )
    2.宁波市第二医院超声科 (浙江 宁波 315000 )

收稿日期: 2024-07-22

  网络出版日期: 2025-01-14

基金资助

浙江省医药卫生科技计划项目(2022RC066)

A study on the evaluation of left ventricular systolic dysfunction in patients with early coronary heart disease by using three⁃dimensional speckle tracking imaging technology combined with left ventricular pressure strain loop

  • Baibing YE ,
  • Xiujuan LI ,
  • Saijun CHEN
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  • Health Science Center,Ningbo University,Ningbo 315211,Zhejiang,China

Received date: 2024-07-22

  Online published: 2025-01-14

摘要

目的 分析三维斑点追踪成像技术联合左室压力-应变环对冠心病早期患者左心室收缩功能减退的评估价值。 方法 选取2022年2月到2024年2月医院收治的97例冠心病早期患者为研究对象,依照左心室收缩功能减退情况分为无左心室收缩功能减退(LVEF值≥ 50%),左心室收缩功能减退(LVEF值< 50%)。所有患者均行临床资料收集、左室压力-应变环、三维斑点追踪成像技术检查。 结果 两组体质量指数、性别、合并糖尿病、高血脂对比差异无统计学意义(P > 0.05),具有可比性;与无左心室收缩功能减退组相比,左心室收缩功能减退组年龄较大,Killip分级Ⅲ-Ⅳ级、多支冠状动脉病变占比较高(P < 0.05)。与左心室无收缩功能减退组相比,左心室收缩功能减退组GWE、GCW、GWI绝对值水平较低,GWW绝对值水平较高(P < 0.05)。与无左心室收缩功能减退组相比,左心室收缩功能减退组面积、圆周、径向、纵向应变水平较低(P < 0.05)。GWE、GCW、GWI、面积、圆周、径向、纵向应变水平与左心室收缩功能减退发生率呈负相关,GWW与左心室收缩功能减退发生率呈正相关(P<0.05)。ROC分析结果显示,左室压力-应变环、三维斑点追踪成像技术预测冠心病早期患者左心室收缩功能减退的敏感度、准确度低于联合检测(P < 0.05)。 结论 左心室收缩功能减退的冠心病早期患者面积、圆周、径向、纵向应变、GWE、GCW、GWI绝对值水平较低,GWW绝对值水平较高,而上述指标均与左心室收缩功能减退发生率相关,三维斑点追踪成像技术联合左室压力-应变环预测冠心病早期患者左心室收缩功能减退的价值较高。

本文引用格式

叶白冰 , 李秀娟 , 陈赛君 . 三维斑点追踪成像技术联合左室压力-应变环对冠心病早期患者左心室收缩功能减退的评估价值[J]. 实用医学杂志, 2025 , 41(1) : 108 -113 . DOI: 10.3969/j.issn.1006-5725.2025.01.018

Abstract

Objective We tried to analyze the value of three-dimensional speckle tracking imaging technology combined with left ventricular pressure strain loop for evaluation of left ventricular systolic dysfunction in early coronary heart disease patients. Methods 97 patients with early coronary heart disease admitted to our hospital from February 2022 to February 2024 were selected as the research subjects. According to the degree of left ventricular systolic dysfunction, they were divided into those without left ventricular systolic dysfunction (LVEF value ≥ 50%) and those with left ventricular systolic dysfunction (LVEF value < 50%). All patients underwent clinical data collection, left ventricular pressure strain loop, and three-dimensional speckle tracking imaging technology examination. Results Body mass index, gender, diabetes mellitus and hyperlipidemia were compared between the two groups (P > 0.05). Compared with the group without left ventricular systolic dysfunction, the group with left ventricular systolic dysfunction is older, with a higher proportion of Killip grades Ⅲ~Ⅳ and multiple coronary artery lesions (P < 0.05). Compared with the group without reduced left ventricular systolic function, the absolute levels of GWE, GCW, and GWI in the group with reduced left ventricular systolic function were lower, while the absolute level of GWW was higher (P < 0.05). Compared with the group without left ventricular systolic dysfunction, the left ventricular systolic dysfunction group had lower levels of area, circumference, radial, and longitudinal strain (P < 0.05). GWE、GCW、GWI、 Area, circumference, radial, and longitudinal strain levels were negatively correlated with the incidence of left ventricular systolic dysfunction, while GWW was positively correlated with the incidence of left ventricular systolic dysfunction (P < 0.05). The ROC analysis results showed that the sensitivity and accuracy of left ventricular pressure strain loop and three-dimensional speckle tracking imaging technology in predicting left ventricular systolic dysfunction in early coronary heart disease patients were lower than combined detection (P<0.05). Conclusions Early coronary heart disease patients with reduced left ventricular systolic function had lower absolute levels of area, circumference, radial, longitudinal strain, GWE, GCW, and GWI, and higher absolute levels of GWW. These indicators are all related to the incidence of left ventricular systolic dysfunction. The combination of three-dimensional speckle tracking imaging technology and left ventricular pressure strain loop had high value in predicting left ventricular systolic dysfunction in early coronary heart disease patients.

参考文献

1 SHARIFOV O F, MURPHY J M, PERRY G J, et al. Echocardiographic diagnosis of left ventricular diastolic dysfunction: Impact of coronary artery disease[J]. Echocardiography, 2021,38(2):197-206. doi:10.1111/echo.14959
2 FARJANA J, RAHMAN M A, RAHMAN M M, et al. Association of Diastolic Dysfunction with Angiographic Severity of Coronary Artery Disease in patients with Non-ST Elevation Myocardial Infarction[J]. Mymensingh Med J, 2022,31(3):773-778.
3 MALOBRRTI A, BOSSI I, TASSISTRO E, et al. Uric acid in chronic coronary syndromes: Relationship with coronary artery disease severity and left ventricular diastolic parameter[J]. Nutr Metab Cardiovasc Dis, 2021,31(5):1501-1508. doi:10.1016/j.numecd.2021.01.023
4 YANG X, REN S, LIU Y, et al. Exploration on the Value of Circulation Quality Control Intervention Mode in Percutaneous Coronary Intervention in Patients with Coronary Heart Disease and Chronic Heart Failure[J]. Heart Surg Forum, 2023,26(6):889-895. doi:10.59958/hsf.7037
5 LI S, WAN F, ZENG R, et al. Clinical Application Value of left Ventricular Pressure-Strain Loop Examination of Myocardial Dysfunction in Patients with Hypertension at Various Risk Levels[J]. Altern Ther Health Med, 2023,29(8):856-862.
6 NASER N, STANGKOVIC I, NESKOVIC A. The Reliability of Automated Three-Dimensional Echocardiography-HeartModel A.I.Versus 2D Echocardiography Simpson Methods in Evaluation of Left Ventricle Volumes and Ejection Fraction in Patients With Left Ventricular Dysfunction[J]. Med Arch, 2022,76(4):259-266. doi:10.5455/medarh.2022.76.259-266
7 中华医学会,中华医学会杂志社,中华医学会全科医学分会,等. 稳定性冠心病基层诊疗指南(2020年)[J]. 中华全科医师杂志,2021,20(3):265-273.
8 FORREST I S, PETRAZZINI B O, DUFFY á, et al. Machine learning-based marker for coronary artery Disease: derivation and validation in two longitudinal cohorts[J]. Lancet, 2023,401(2):215-225. doi:10.1016/s0140-6736(22)02079-7
9 GOVARDI E, YU L L, HABIB F, et al. Microalbuminuria and mortality in individuals with coronary heart disease: A meta-analysis of a prospective study[J]. Indian Heart J, 2023,75(4):229-235. doi:10.1016/j.ihj.2023.05.006
10 汪宇,缪莹,林强,等. 甘油三酯葡萄糖指数联合腰围对泸州地区中老年人群10年新发冠心病的前瞻性队列研究[J]. 实用医学杂志,2024,40(12):1731-1736.
11 GAO Y, ZHANG Y, TANG Y, et al. Myocardial work and energy loss of left ventricle obtained by pressure-strain loop and vector flow mapping: A new perspective on idiopathic left bundle branch block[J]. Quant Imaging Med Surg, 2023,13(1):210-223. doi:10.21037/qims-22-284
12 LIANG Z, YANG Y, WANG F, et al. Assessing the early prognosis of heart failure after acute myocardial infarction using left ventricular pressure-strain loop: A prospective randomized controlled clinical Study[J]. Quant Imaging Med Surg, 2024,14(2):1957-1970. doi:10.21037/qims-23-1079
13 TAKEUCHI M, NABESHUMA Y, KITANO T, et al. Prognostic value of the left ventricular-left atrial volume ratio assessed using three-dimensional echocardiography with fully automated analytical software[J]. J Cardiol, 2021,78(5):406-412. doi:10.1016/j.jjcc.2021.05.004
14 LEI C, ZHU X, HSI D H, et al. Predictors of cardiac involvement and survival in patients with primary systemic light-chain amyloidosis: Roles of the clinical, chemical, and 3-D speckle tracking echocardiography parameters[J]. BMC Cardiovasc Disord, 2021,21(1):43. doi:10.1186/s12872-021-01856-3
15 刘艳红,王飞,杨亚娟,等. 左心室压力-应变环评估急性心肌梗死患者经皮冠状动脉介入术后心肌收缩功能和灌注水平[J]. 中华超声影像学杂志,2022,31(2):115-121.
16 陈佳易,袁帅,胡胜男,等. 左心室压力-应变环联合Tei指数评价慢性中重度主动脉瓣反流患者左心功能的初步研究[J]. 中华医学超声杂志(电子版),2023,20(12):1231-1236.
17 王小贤,陈明龙,梁希晨,等. 基于左心室压力-应变环对射血分数保留心力衰竭合并持续性心房颤动患者射频消融术后心功能的定量评估[J]. 中华心律失常学杂志,2022,26(2):159-164.
18 LIU Y, CUI C, LI Y, et al. Predictive value of the echocardiographic noninvasive myocardial work index for left ventricular reverse remodeling in patients with multivessel coronary artery disease after percutaneous coronary intervention[J]. Quant Imaging Med Surg, 2022,12(7):3725-3737. doi:10.21037/qims-21-1066
19 RAN H, YAO Y, WAN L, et al. Characterizing stenosis severity of coronary heart disease by myocardial work measurement in patients with preserved ejection fraction[J]. Quant Imaging Med Surg, 2023,13(8):5022-5033. doi:10.21037/qims-22-955
20 高晓梅,王显悦,张本,等. 左室压力-应变环评估冠心病患者经皮冠状动脉介入术前后心肌做功的临床研究[J]. 现代生物医学进展,2021,21(22):4308-4312.
21 PAN J C, LYU L J, LIU Q D, et al. Association between resting myocardial work indices and stress myocardial perfusion in patients with angina and non-obstructive coronary artery Disease[J]. Quant Imaging Med Surg, 2023,13(7):4563-4577. doi:10.21037/qims-22-321
22 ZHANG L, WANG Y, XIAO W, et al. Evaluation of left ventricular function of pregnant women with autoimmune diseases using speckle tracking echocardiography[J]. Int J Cardiovasc Imaging, 2023,39(9):1643-1655. doi:10.1007/s10554-023-02876-0
23 丁静,刘表虎,纪文艳,等. 实时三维超声联合斑点追踪成像技术评价二尖瓣修复术后左心室结构与功能改变的临床价值[J]. 皖南医学院学报,2023,42(2):154-158.
24 SUN M, XING Y, GUO Y, et al. Left atrial reservoir strain is an outstanding predictor of adverse cardiovascular outcomes in patients undergoing maintenance hemodialysis: Assessment via three-dimensional speckle tracking Echocardiography[J]. Clin Cardiol, 2022,45(5):549-557. doi:10.1002/clc.23815
25 朵天军,朱战英,赵彩虹,等. 3D-STI下左心房功能参数与冠状动脉病变严重程度的相关性[J]. 中南医学科学杂志,2023,51(6):946-948.
26 蔡琦,雍永宏,何花,等. 三维斑点追踪技术联合血清同型半胱氨酸对冠心病患者左心功能的评估价值[J]. 中华临床医师杂志(电子版),2022,16(5):425-430.
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