综述

心率恢复在心血管疾病评估的应用价值及进展

  • 杨雅琳 ,
  • 胡阳 ,
  • 魏云鸿 ,
  • 邓洁 ,
  • 王煜
展开
  • 昆明医科大学附属延安医院全科医学科 (昆明 650000 )

收稿日期: 2023-12-16

  网络出版日期: 2024-09-30

基金资助

云南省卫生健康委员会医学后备人才培养经费支持项目(H-2019022);昆明市卫生科技人才培养项目暨“十百千”工程培养经费支持项目(编号:2019-sw[省]-01)

Application value and progress of heart rate recovery in indication of cardiovascular diseases

  • Yalin YANG ,
  • Yang HU ,
  • Yunhong WEI ,
  • Jie DENG ,
  • Yu. WANG
Expand
  • Department of General Medicine,Yan'an Hospital Affiliated to Kunming Medical University,Kunming 650000,China

Received date: 2023-12-16

  Online published: 2024-09-30

摘要

心率恢复是指运动期间达到的最高心率与运动停止后一段时间内心率的差值,是目前临床上评价自主神经系统功能最常使用的指标之一,具有无创、可重复的优点。目前,心率恢复在价心血管系统疾病中的应用十分广泛,临床上可运用心率恢复评估心血管系统疾病患者疾病的严重程度、预后情况、发生心血管事件风险、死亡率等,该文主要就心率恢复在心血管疾病中的应用价值及目前研究进展等方面展开论述。

本文引用格式

杨雅琳 , 胡阳 , 魏云鸿 , 邓洁 , 王煜 . 心率恢复在心血管疾病评估的应用价值及进展[J]. 实用医学杂志, 2024 , 40(18) : 2660 -2664 . DOI: 10.3969/j.issn.1006-5725.2024.18.026

Abstract

Heart rate recovery, a widely used indicator in clinical evaluation of the autonomic nervous system, refers to the difference between maximum heart rate during exercise and the heart rate after 1 or a few minutes of cessation. It possesses advantages of being noninvasive and repeatable. Currently, heart rate recovery is extensively applied in cardiovascular diseases for evaluating disease severity, prognosis, risk of cardiovascular events, and mortality. This article primarily discusses the application value and current research progress of heart rate recovery in cardiovascular diseases.

参考文献

1 《中国心血管健康与疾病报告2022》编写组. 《中国心血管健康与疾病报告2022》要点解读[J]. 中国心血管杂志, 2023,28(4):297-312.
2 HERNESNIEMI J A, SIPIL? K, TIKKAKOSKI A, et al. Cardiorespiratory fitness and heart rate recovery predict sudden cardiac death independent of ejection fraction[J]. Heart, 2020,106(6):434-440. doi:10.1136/heartjnl-2019-315198
3 PECANHA T, SILVA-JUNIOR N D, FORJAZ C L. Heart rate recovery: autonomic determinants, methods of assessment and association with mortality and cardiovascular diseases[J]. Clin Physiol Funct Imaging, 2014,34(5):327-339. doi:10.1111/cpf.12102
4 TAN J, YANG M, WANG H, et al. Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch[J]. Cell Rep, 2022,38(10):110468. doi:10.1016/j.celrep.2022.110468
5 VAN D E VEGTE Y J, VAN DER HARST P, VERWEIJ N. Heart Rate Recovery 10 Seconds After Cessation of Exercise Predicts Death[J]. J Am Heart Assoc, 2018,7(8):e8341.
6 JAE S Y, KURL S, LAUKKANEN J A, et al. Relation of heart rate recovery after exercise testing to coronary artery calcification[J]. Ann Med, 2017,49(5):404-410. doi:10.1080/07853890.2017.1292044
7 VOLKAN EMREN S, GEDIZ R B, ?EN?Z O, et al. Decreased heart rate recovery may predict a high SYNTAX score in patients with stable coronary artery disease[J]. Bosn J Basic Med Sci, 2019,19(1):109-115. doi:10.17305/bjbms.2019.3725
8 LACHMAN S, TERBRAAK M S, LIMPENS J, et al. The prognostic value of heart rate recovery in patients with coronary artery disease: A systematic review and meta-analysis[J]. Am Heart J, 2018,199:163-169.
9 KURL S, JAE S Y, VOUTILAINEN A, et al. Exercise heart rate reserve and recovery as risk factors for sudden cardiac death[J]. Prog Cardiovasc Dis, 2021,68:7-11.
10 KIM B J, JO E A, IM S I, et al. Heart rate recovery and blood pressure response during exercise testing in patients with microvascular angina[J]. Clin Hypertens, 2019,25:4.
11 GIGA V, BOSKOVIC N, DJORDJEVIC-DIKIC A, et al. Heart Rate Recovery as a Predictor of Long-Term Adverse Events after Negative Exercise Testing in Patients with Chest Pain and Pre-Test Probability of Coronary Artery Disease from 15% to 65[J]. Diagnostics (Basel), 2023,13(13):2229. doi:10.3390/diagnostics13132229
12 JUNG M H, IHM S H, LEE D H, et al. Prehypertension is a comorbid state with autonomic and metabolic dysfunction[J]. J Clin Hypertens (Greenwich), 2018,20(2):273-279.
13 INANC I H, SABANOGLU C. The relationship of masked hypertension with autonomic dysfunction and cardiometabolic parameters: a case-control study[J]. Eur Rev Med Pharmacol Sci, 2022,26(17):6265-6272.
14 VERMA S, BHATI P, AHMAD I, et al. Co-Existence of hypertension worsens post-exercise cardiac autonomic recovery in type 2 diabetes[J]. Indian Heart J, 2018,70(Suppl 3):S82-S89.
15 YU Y, LIU T, WU J, et al. Heart rate recovery in hypertensive patients: relationship with blood pressure control[J]. J Hum Hypertens, 2017,31(5):354-360.
16 ZHAO Y, ZHENG Y, MA X, et al. Low-Intensity Resistance Exercise Combined With Blood Flow Restriction is More Conducive to Regulate Blood Pressure and Autonomic Nervous System in Hypertension Patients-Compared With High-Intensity and Low-Intensity Resistance Exercise[J]. Front Physiol, 2022,13:833809.
17 WANG J, FANG F, YIP G W, et al. Importance of chronotropic response and left ventricular long-axis function for exercise performance in patients with heart failure and preserved ejection fraction[J]. Int J Cardiol, 2016,202:339-343.
18 壮可, 赵燕, 张云梅, 等. 射血分数保留心力衰竭患者心率恢复与运动耐量及预后的关系[J]. 中华心力衰竭和心肌病杂志(中英文), 2019,3(3):129-133.
19 PEARSON M J, SMART N A. Exercise therapy and autonomic function in heart failure patients: a systematic review and meta-analysis[J]. Heart Fail Rev, 2018,23(1):91-108. doi:10.1007/s10741-017-9662-z
20 SABBAG A, BERKOVITCH A, SIDI Y, et al. Poor Heart Rate Recovery Is Associated With the Development of New-Onset Atrial Fibrillation in Middle-Aged Adults[J]. Mayo Clin Proc, 2016,91(12):1769-1777. doi:10.1016/j.mayocp.2016.08.012
21 KUYUMCU M S, OZEKE O, CAY S, et al. The short-term impact of the catheter ablation on noninvasive autonomic nervous system parameters in patients with paroxysmal atrial fibrillation[J]. Pacing Clin Electrophysiol, 2017,40(11):1193-1199. doi:10.1111/pace.13179
22 DONNELLAN E, WAZNI O M, CHUNG M K, et al. Attenuated heart rate recovery is associated with higher arrhythmia recurrence and mortality following atrial fibrillation ablation[J]. Europace, 2021, 23(7):1063-1071.
23 LIEVE K, DUSI V, VAN DER WERF C, et al. Heart Rate Recovery After Exercise Is Associated With Arrhythmic Events in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia[J]. Circ Arrhythm Electrophysiol, 2020,13(3):e7471.
24 LUNDSTR?M A, WIKLUND U, LAW L, et al. Aberrant autonomic pattern during the post-exercise recovery phase in long QT syndrome patients[J]. Auton Neurosci, 2021,236:102897.
25 GABA P, PEDROTTY D, DESIMONE C V, et al. Mortality in Patients With Right Bundle-Branch Block in the Absence of Cardiovascular Disease[J]. J Am Heart Assoc, 2020,9(19):e17430. doi:10.1161/jaha.120.017430
26 PATEL V, CRITOPH C H, FINLAY M C, et al. Heart Rate Recovery in Patients With Hypertrophic Cardiomyopathy[J]. Am J Cardiol, 2014,113(6):1011-1017.
27 LUO H, DIMAANO V L, KEMBRO J M, et al. Exercise Heart Rates in Patients With Hypertrophic Cardiomyopathy[J]. Am J Cardiol, 2015,115(8):1144-1150. doi:10.1016/j.amjcard.2015.01.548
28 MASRI A, PIERSON L M, SMEDIRA N G, et al. Predictors of long-term outcomes in patients with hypertrophic cardiomyopathy undergoing cardiopulmonary stress testing and echocardiography[J]. Am Heart J, 2015, 169(5): 684-692.e1.
29 SHINODA N, HIRASHIKI A, OKUMURA T, et al. Predictive Value of Heart Rate Recovery after Exercise Testing in Addition to Brain Natriuretic Peptide Levels in Ambulatory Patients with Nonischemic Dilated Cardiomyopathy: Predictive Value of Heart Rate Recovery[J]. Ann Noninvasive Electrocardiol, 2012, 17(4):378-386. doi:10.1111/j.1542-474x.2012.00542.x
30 GIARDINI A, FENTON M, DERRICK G, et al. Impairment of heart rate recovery after peak exercise predicts poor outcome after pediatric heart transplantation[J]. Circulation, 2013,128(11 ):S199-S204.
31 REZENDE C F, MANCUZO E V, CORREA R A. Heart rate recovery in 1 minute after the 6-minute walk test predicts adverse outcomes in pulmonary arterial hypertension[J]. PLoS One, 2022,17(5):e268839. doi:10.1371/journal.pone.0268839
32 SHWAISH N S, MALLOY-WALTON L, FELDMAN K, et al. Heart Rate Recovery Following Exercise Testing in Pediatric Patients with Acyanotic Repaired Congenital Heart Disease[J]. Pediatr Cardiol, 2022,43(4):790-795.
33 ALEKSANDROWICZ K A, ALEKSANDROWICZ K M, WITKOWSKI T G, et al. Early Heart Rate Recovery after a 6-min Walking Test Predicts Clinical Benefits in Patients after Percutaneous Aortic Valve Implantation[J]. Int J Environ Res Public Health, 2023,20(5):4270.
文章导航

/