收稿日期: 2024-04-01
网络出版日期: 2024-09-13
基金资助
国家自然科学基金项目(81974081);梅州市人民医院培育项目(PY-C20210020);梅州市科技计划项目(2022B47)
Mechanism and research progress of dexmedetomidine in improving perioperative neurocognitive disorder in frail elderly patients
Received date: 2024-04-01
Online published: 2024-09-13
徐志燕 , 陈伟元 , 姚伟锋 . 右美托咪定改善衰弱老年围术期神经认知障碍的机制及研究进展[J]. 实用医学杂志, 2024 , 40(17) : 2503 -2507 . DOI: 10.3969/j.issn.1006-5725.2024.17.025
With the acceleration of population aging and the continuous growth of the elderly population， frailty has become a global public health problem. At the same time， an increasing number of elderly people require surgical treatment， and people are paying more attention to the possible postoperative neurocognitive disorder. Frailty and neurocognitive disorder interact with each other， forming a vicious cycle. Improving one of them can improve the prognosis of the elderly. As one of the commonly used anesthetic drugs in clinical practice， dexmedetomidine has neuroprotective effects.This article reviews the relationship between frailty and neurocognitive disorder， as well as the research progress of dexmedetomidine in improving perioperative neurocognitive disorder in frail elderly patients.
Key words： dexmedetomidine; frailty; perioperative neurocognitive disorder
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