临床新进展

“长新冠”患者疲劳的机制研究进展

  • 关巧妍 ,
  • 包宋羽 ,
  • 崔源源 ,
  • 李思铭
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  • 1.山西中医药大学 (太原 030024 )
    2.中国中医科学院西苑医院心血管科 (北京 100091 )
李思铭,副主任医师,医学博士,硕士研究生导师。入选中国中医科学院优秀青年科技人才。兼任中国中西医结合学会循证医学专业委员会青年委员,中国中医药研究促进会中西医结合心血管病预防与康复专业委员会心力衰竭学组委员,中国中医药研究促进会青年医师分会常务理事。致力于中西医结合防治冠心病、心衰、动脉硬化、高血压、血脂代谢异常、心律失常等心血管疾病临床及研究。主持国家自然科学基金项目1项,参加国家及省部级课题10余项,研究成果获中西医结合学会科技进步二等奖1项。在国内外知名期刊发表中英文学术论文20余篇,SCI收录10余篇。参与编写《中医心脏病学》等多部专著。

收稿日期: 2023-11-21

  网络出版日期: 2024-05-15

基金资助

国家自然科学青年基金项目(82104668);中国中医科学院优秀青年科技人才培养专项(ZZ14-YQ-009);山西省中医药管理局科研项目(2022ZYYC032);山西中医药大学研究生创新创业教育项目(2022YS010)

Research progress of the mechanisms of fatigue in Long COVID patients

  • Qiaoyan GUAN ,
  • Songyu BAO ,
  • Yuanyuan CUI ,
  • Siming. LI
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  • *.Shanxi University of Chinese Medicine,Taiyuan 030024,China

Received date: 2023-11-21

  Online published: 2024-05-15

摘要

自新型冠状病毒感染(COVID-19)以来,许多感染患者出现多个系统症状,而这些症状在感染3个月后仍会存在较长时间,被称为“长新冠(Long COVID)”。大量研究表明疲劳是“长新冠”诸多症状中最常见的症状,已严重影响患者生活质量。因此,了解“长新冠”引起疲劳症状的机制尤为重要。本文通过梳理相关文献,总结“长新冠”疲劳的可能机制,包括免疫反应、氧化应激、影响中枢神经系统等,旨在提高临床对“长新冠”引起疲劳的认识,并为其治疗提供一定的思路。

关键词: 长新冠; 疲劳; 机制

本文引用格式

关巧妍 , 包宋羽 , 崔源源 , 李思铭 . “长新冠”患者疲劳的机制研究进展[J]. 实用医学杂志, 2024 , 40(9) : 1186 -1190 . DOI: 10.3969/j.issn.1006-5725.2024.09.002

Abstract

Since COVID?19 infection, many infected patients have developed multiple systemic symptoms that persist long after 3 months of infection, which is called Long COVID. Numerous studies have shown that fatigue is the most common symptom among the many symptoms of Long COVID that has severely impacted the quality of their life. Therefore, it is particularly important to understand the mechanisms by which Long COVID causes fatigue symptoms. This article summarizes the possible mechanisms of Long COVID fatigue, including immune response, oxidative stress, and affecting the central nervous system, by combing through the relevant literature, aiming to increase clinical awareness of fatigue induced by Long COVID and to provide certain ideas for its treatment.

Key words: Long COVID; fatigue; mechanisms

参考文献

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