目的 分析 2016-2021 年淄博市宫颈癌发病、死亡情况及疾病负担变化趋势，为开展宫颈癌 防治提供建议。方法 分析 2016-2021 年淄博市宫颈癌（ICD⁃10）发病和死亡资料，计算发病、死亡及疾病 负担指标。结果 淄博市宫颈癌发病率由 2016 年的 14.77/10 万升至 2021 年的 17.54/10 万（APC =4.51%， t = 3.37，P = 0.028）；标化发病率由 12.13/10 万升至 14.83/10 万（APC = 4.85%，t = 3.92，P = 0.017）；发病率随 年龄增长先升高后降低，45～54 岁组发病率升至高峰。沂源县 25～44 岁年龄组发病率由 2016 年的 12.60/ 10 万升至 2021 年的 30.63/10 万（APC = 24.73%，t = 3.87，P = 0.018）。宫颈癌病死率随年龄增长而升高。 2016-2021 年宫颈癌所致伤残损失寿命年（YLD）率由 0.72‰升到 0.86‰，年度变化百分比（APC）为 4.50%； 城市中宫颈癌所致伤残调整寿命年（DALY）率高于农村；城市与农村宫颈癌所致过早死亡损失寿命年 （YLL）率在 DALY 率中的占比均呈下降趋势，APC 分别为-3.70%、-5.40%；城市与农村宫颈癌所致 YLD 率 在伤残调整寿命年（DALY）率中的占比均呈上升趋势，APC 分别为 2.44%、4.59%。结论 淄博市宫颈癌发 病、死亡水平较高，发病率及 YLD 率呈上升趋势，城市中宫颈癌所致 DALY 率高于农村，应进一步加强宫 颈癌防治工作。 

Objective To analyze the incidence and death of cervical cancer and the changing trend of disease burden from 2016 to 2021 in Zibo City，and to provide suggestions for the prevention and treatment of cervi⁃ cal cancer. Methods The incidence and mortality data of cervical cancer（ICD ⁃10）in Zibo City from 2016 to 2021 were analyzed，and the indicators of incidence，mortality and disease burden were calculated. Results The incidence rate of cervical cancer in Zibo was increased from 14.77/100 000 in 2016 to 17.54/100 000 in 2021 （APC = 4.51%，t = 3.37，P = 0.028）. The standardized incidence rate was increased from 12.13/100 000 to 14.83/ 100 000（APC = 4.85%，t = 3.92，P = 0.017）. The incidence was increased first and then decreased with age， and peaked in the age group of 45 ~ 54 years. The incidence rate in the 25 ~ 44 years old age group in Yiyuan County was increased from 12.60/100 000 in 2016 to 30.63/100 000 in 2021（APC = 24.73%，t = 3.87，P = 0.018）. The mortality rate of cervical cancer was increased with age. From 2016 to 2021，the YLD rate caused by cervical cancer was increased from 0.72‰ to 0.86‰，and the APC was 4.50%. DALY rate of cervical cancer in urban areas was higher than that of the rural areas. The proportion of YLL rate in DALY rate of cervical cancer in urban and rural areas showed a downward trend，APC were -3.70% and -5.40%，respectively. The proportion of YLD rate in DALY rate caused by cervical cancer in urban and rural areas showed an upward trend，APC was 2.44% and 4.59%，respectively. Conclusion The incidence and mortality of cervical cancer in Zibo city were high，and the incidence and YLD rate showed an increasing trend. The DALY rate caused by cervical cancer in urban area was higher than that of the rural area. It is necessary to further strengthen the prevention and control of cervical cancer.