目的 探索经颅微电流刺激对乳腺癌根治术患者围术期焦虑的影响。方法 选取择期行乳 腺癌根治术患者86例，按随机数字表法分为干预组和对照组各43例：干预组在术前2 d、术前1 d、手术等待 区、术后1 d、术后3 d进行5次20 min经颅微电流刺激，对照组给予同时间点的5次20 min假刺激。在术前 2 d（T1）、手术等待区（T2）、术后1 d（T3）、术后3 d（T4）、术后7 d（T5）采用状态⁃特质焦虑量表和阿森斯失眠量 表评估患者焦虑和睡眠情况，记录术中情况、术后不良反应。结果 两组术前基线水平、术中情况和术后不 良反应发生率差异无统计学意义（P > 0.05）。在T2、T3、T4、T5，干预组较对照组有更低的焦虑和失眠评分，差 异有统计学意义（P < 0.05）。结论 经颅微电流刺激对改善乳腺癌根治术患者围术期焦虑有积极作用，并在一定程度上改善患者睡眠，该技术为乳腺癌根治术患者围术期抗焦虑和改善睡眠等非药物干预提供证据。 

Objective To investigate the effects of cranial electrotherapy stimulation on perioperative anxiety in patients undergoing radical mastectomy. Methods A total of 86 patients undergoing radical mastectomy were randomly divided into intervention group（n = 43）and control group（n = 43）. The intervention group was treated with cranial electrotherapy stimulation for five times：2 and 1 day before operation，right before operation at the waiting chamber，1 and 3 days after operation，20 minutes each time，while the control group was given sham stim⁃ ulation in the same way at the same time points. State⁃trait anxiety inventory and Athens Insomnia Scale were used to evaluate the patients′ anxiety and state of sleep at 2 days before operation（T1），right before operation at the waiting chamber（T2），1 day（T3），3 days（T4）and 7 days（T5）after operation，and the intraoperative conditions and postoperative adverse reactions were observed. Results There were no statistically significant differences between the two groups in terms of the preoperative baseline levels，intraoperative conditions，and incidence of postoperative adverse events. At T2，T3，T4，and T5，the scores of anxiety and insomnia in the intervention group were significantly lower than those of the control group（P < 0.05）. Conclusion Cranial electrotherapy stimulation has a positive effect in alleviating perioperative anxiety of patients undergoing radical mastectomy and can effectively improve patients′ sleep quality. This technique provides evidence for perioperative non⁃drug interventions in anxiety and poor sleep of patients undergoing radical mastectomy.