利用 3D 打印技术制造的新型仿生脊髓支架具有良好的生物相容性和力学性能，可以有效 改善脊髓损伤（spinal cord injury，SCI）后产生的微环境紊乱和胶质瘢痕问题，通过联合特定的神经细胞还 可以使 SCI 的修复更加具有针对性和特异性。近年来，许多新型脊髓支架及其相应的治疗方法被研发出 来，包括以胶原蛋白为基础混合其他材料进行改良的新型支架、新型化合材料脊髓支架和支架载特定因 子修饰的神经细胞的新型治疗思路等，通过动物实验验证了治疗方法的可行性，为临床 SCI 的修复治疗提 供了新的方向。本文就3D 打印仿生支架在脊髓损伤修复中的实验研究进展进行综述。

The new biomimetic spinal cord scaffold manufactured by 3D printing has good biocompatibility and mechanical properties，which can effectively improve the microenvironment disorder and glial scar problems after spinal cord injury（SCI）. By combining specific nerve cells，the repair of SCI can also be more targeted and specific. In recent years，many new spinal scaffolds and their corresponding treatment methods have been devel⁃ oped，including new scaffolds based on collagen and improved by mixing other materials，new synthetic materials spinal scaffolds and new treatment ideas of nerve cells modified by specific factors on scaffolds. The feasibility of the treatment methods has been verified through animal experiments，which provides a new direction for the repair and treatment of SCI. This article reviews the experimental research progress of 3D printed biomimetic scaffolds in the repair of spinal cord injury.