烫伤是一种创伤后炎症性疾病，多器官衰竭是烫伤后死亡的主要原因，过度的全身和局部 炎症直接导致终末器官损伤。肝脏是人体最大的代谢和解毒器官，极易遭受内毒素的攻击，肝功能的恶 化会导致烫伤患者的发病率和死亡率增高，因此严重烫伤后肝损伤的修复意义重大。尽管烫伤的临床管 理取得了显著进展，但目前严重烫伤的治疗仍有较大的局限性。近年来，间充质干细胞治疗在组织修复 方面有很大的希望，本综述将重点研究间充质干细胞在烫伤诱导的肝脏损伤方面的作用。

Burn is a post⁃traumatic inflammatory disease. Multiple organ failure is the main cause of death after burn. Excessive systemic and local inflammation directly leads to terminal organ injury. Liver is the largest metabolic and detoxification organ of the human body，and it is easy to be attacked by endotoxin. The deterioration of liver function will lead to increased morbidity and mortality of burn patients. Therefore，the repair of hepatic injury after severe burn is of great significance. Although progress has been made in the clinical management of burns， there are still limitations in the treatment of severe burns. In recent years，Mesenchymal stem cells（MSCs）have shown great promise in tissue repair. In this review，we will focus on the role of MSCs in severe burn⁃induced hepatic injury.