目的 探讨 MAP 洗涤红细胞（MAP washes the red blood cells，Map WBC）及生理盐水混悬洗 涤红细胞（normal saline mixed with red blood cells，WBC）对直接抗人球蛋白试验（direct antiglobulin test， DAT）阳性患者输血治疗的疗效分析。方法 选择 2020 年 1 月至 2021 年 12 月本院 207 例直接抗人球蛋白 试验阳性患者，分为 MAP 组（n = 93）和盐水组（n = 114），MAP 组输注 MAP 洗涤红细胞治疗，盐水组输注生 理盐水混悬洗涤红细胞治疗，通过检测血红蛋白（hemoglobin，HGB）和胆红素（total bilirubin，TBIL）实验室 指标观察两组患者的输血疗效，同时对输血不良反应进行观察。结果 对两组患者输血前后各指标变化 程度进行比较，组内 HGB 和 TBIL 明显升高，差异有统计学意义（P < 0.05），组间 HGB 和 TBIL 变化不明显， 差异无统计学意义（P > 0.05），且两组输血均无不良反应发生。结论 DAT 阳性患者输注两种洗涤红细 胞均安全有效，但MAP 洗涤红细胞由于保存时间长，更能满足临床急诊需求。

Objective To investigate the efficacy of MAP washed red blood cells（MAP WBC）and normal saline mixed with red blood cells（WBC）on direct antiglobulin test（DAT）of blood transfusion therapy in DAT⁃ positive patients. Methods From January 2020 to December 2021，207 DAT ⁃ positive patients in our hospital were selected and divided into MAP group（n = 93）and saline group（n = 114）. MAP group was infused with MAP washed red blood cells for treatment，while saline group was treated by infusion of saline and washed red blood cells mixture. The blood transfusion efficacy as well as side effects of the two groups was observed via detecting the laboratory indexes of hemoglobin（HGB）and total bilirubin（TBIL）. Results Comparing the changes of each index before and after blood transfusion in the two groups，inner⁃group HGB and TBIL significantly increased，and the difference was statistically significant（P < 0.05），while there was no obvious change in HGB and TBIL between the two groups and the difference was not statistically significant（P > 0.05）. There were no adverse reactions of blood transfusion in both groups. Conclusion Both types of washed red blood cells are safe and effective for DAT⁃ positive patients，but MAP washed red blood cells can better meet the needs of clinical emergency with the capabil⁃ ity to be stored for longer period.