目的 回顾性分析经皮椎体成形术术中骨水泥椎间隙渗漏对临床疗效及椎间盘高度和角度的中期影响。方法 选取本院收治的骨质疏松椎体压缩性骨折病人 76 例，分为渗漏组（n = 36）和无渗漏组（n = 40），每个病例均评估术后院内及末次随访的 VAS 和 ODI 评分，并测量椎间隙前缘、中部、后缘的高度及伤椎节段Cobb 角，计算椎间隙总和高度，先行各组内前后对比各指标的差异，然后再计算随访前后高度差值、前后 Cobb 角差值、前后 VAS 及 ODI 差值，组间横向比较两组差值有无差异。结果 渗漏组组内随访前后配对 t 检验得出椎间隙高度、Cobb 角、VAS 及 ODI 评分差异均无统计学意义，无渗漏组组内随访前后配对 t 检验得出椎间隙高度、Cobb 角、VAS 及 ODI 评分差异均无统计学意义，两组间独立样本 t 检验得出随访前后椎间隙总和高度的差值、Cobb 角的差值、VAS 差值及 ODI 差值差异均无统计学意义。结论 经皮椎体成形术中骨水泥椎间隙渗漏没有带来术后中期椎间盘高度、角度及临床疗效的明显变化。

Objective To retrospectively analyze the medium ⁃term effects of bone cement vertebral gap leakage on the clinical efficacy and the disc height and angle during percutaneous vertebroplasty. Methods 76 patients with osteoporosis compressive fracture admitted to our hospital were divided into a leakage group（n = 36）and a leakage⁃free group（n = 40）. The VAS and ODI scores were assessed in each patient during hospitalization and final follow⁃up. The height of the anterior，central，and posterior edges of vertebral gap，and the Cobb angle of the impaired vertebral segments were measured，and the total height of the vertebral gap was calculated. The difference in the indexes was compared in each group，the differences of the height，Cobb angle，VAS and ODI were then calculated before and after follow⁃up，the differences between the two groups were compared. Results Paired t⁃test indicated that there were no statistical differences in vertebral gap height，Cobb angle，VAS and ODI scores before and after follow⁃up in both groups. Independent sample t⁃test showed that there were no statistical differences in the difference of total height of the gap，Cobb angle，VAS and ODI between the two groups. Conclusions Bone cement vertebral gap leakage during percutaneous vertebroplasty did not lead to a marked postoperative medium ⁃term change in the disc height and angle and the clinical efficacy.