关键词: 心脏移植, 主动脉内球囊反搏, 围手术期, 术后感染

Abstract:

Objective To investigate the effect of intra ⁃aortic balloon pump treatment on infection after heart transplantation during perioperative period. Methods Clinical data of 112 patients undergoing heart trans⁃ plantation in the 7th People′s Hospital of Zhengzhoufrom May 2018 to October 2021 were retrospectively analyzed. According to whether intra⁃aortic balloon Pump（IABP）treatment as a bridge to heart transplantation，all patients were divided into IABP group（n = 43）and non⁃IABP group（n = 69）. Clinical data were statistically compared between the two groups，and the infection indexes and the incidence of infection in the two groups were analyzed. Results There were no significant differences in general data such as donor age，recipient age，recipient basic diseases，previous diseases，primary diseases，hematological examination and intraoperative data between the two groups（P > 0.05），but the proportion of vasoactive drugs to maintain circulation，ECMO and endotracheal intuba⁃ tion in IABP group was significantly higher than that in non⁃IABP group（P < 0.05），and procalcitonin in IABP group was higher than that in non⁃IABP group. The lymphocyte count was lower than that in IABP group（P < 0.05）， and the leukocyte and neutrophil counts in IABP group were higher than those in non⁃IABP group. There was no significant difference in postoperative total infection incidence and the infection incidence of different systems between the two groups（P > 0.05）. Conclusion IABP treatment as a bridge to heart transplantation does not increase the incidence of early postoperative infections and long⁃term survival. 

Key words:

heart transplantation, intra?aortic balloon pump（IABP）, perioperative stage, postoper? ative infection