实用医学杂志 ›› 2022, Vol. 38 ›› Issue (17): 2185-2190.doi: 10.3969/j.issn.1006⁃5725.2022.17.013

• 临床研究 • 上一篇    下一篇

数字减影血管造影引导下梯度逐级球囊扩张治疗食管癌术后吻合口狭窄的临床研究

杨东强1 李亚洲1 杨光1 时萍2   

  1. 河北医科大学第四医院1 放射科,2 耳鼻喉科(石家庄 050011)

  • 出版日期:2022-09-10 发布日期:2022-09-10
  • 通讯作者: 杨光 E⁃mail:yanggzj@163.com
  • 基金资助:
    河北省医学科学研究课题计划(编号:20220151)

DSA⁃guided graded balloon dilatation in the treatment of anastomotic stenosis after esophagectomy

YANG Dongqiang*,LI Yazhou,YANG Guang,SHI Ping.      

  1. Department of Radiology,the 4th Hospital of Hebei Medical University,Shijiazhuang 050011,China

  • Online:2022-09-10 Published:2022-09-10
  • Contact: YANG Guang E⁃mail:yanggzj@163.com

摘要:

目的 探讨数字减影血管造影(digital subtraction angiography,DSA)引导下梯度逐级球囊扩 张治疗食管癌术后吻合口狭窄的临床效果,总结提升扩张效果的方法及经验。方法 回顾性分析我院 2015 2 月至 2020 5 月期间,69 例食管癌术后吻合口狭窄在 DSA 引导下行梯度逐级球囊扩张治疗患者 的临床资料,依据扩张前后吻合口的大小,评估吞咽困难分级及生存质量评分。结果 DSA引导下梯度逐 级球囊扩张能有效改善食管癌术后吻合口狭窄患者的吞咽困难症状;患者手术方式与吻合口扩张效果无 统计学意义(P > 0.05);球囊扩张与食管癌手术间隔 12 周以内的扩张效果优于间隔 12 周以上的(P < 0.05);前两次球囊扩张时间间隔 2 周以内的效果好于间隔 2 周以上(P < 0.05);扩张 2 次以上的患者的生 存质量评分高于仅扩张 2 次的(P < 0.05)。结论 对于食管癌术后吻合口狭窄,DSA 引导下的梯度逐级球 囊扩张治疗优势明显,术中可通过梯度压力法进行渐进性扩张,选择最合适的扩张终点,手术后12周以内 进行球囊扩张和间隔2周以内进行第二次球囊扩张均可提高吻合口的扩张效果,适当增加扩张的次数,可提高患者的生存质量评分。

关键词:

数字减影血管造影, 球囊扩张术, 食管癌, 术后吻合口狭窄

Abstract:

Objective To investigate the clinical effect of gradient step⁃by⁃step balloon dilatation guided by digital subtraction angiography(DSA)for anastomotic stricture after esophageal cancer surgery. Methods The clinical data of 69 patients with anastomotic stricture after esophageal cancer surgery who underwent DSA guided gradient step⁃by⁃step balloon dilatation from February 2015 to May 2020 in our hospital were retrospectively analyzed. According to the size of anastomotic stoma before and after dilatation,dysphagia grade and quality of life score were assessed. Results DSA guided gradient step⁃by⁃step balloon dilatation effectively improved dysphagia symptoms in patients with anastomotic stricture after esophageal cancer surgery. No statistical significance was found in surgical methods and anastomotic dilatation effect(P > 0.05);the dilatation effect of balloon dilatation and esophageal cancer surgery within 12 weeks was better than that within 12 weeks(P < 0.05);the effect of the first two balloon dilatation time within 2 weeks was better than that at more than 2 weeks(P < 0.05);the quality of life score of patients with more than two dilations was higher than that of patients with only two dilations(P < 0.05). Conclusion For anastomotic stricture after esophageal cancer surgery,DSA guided gradient step⁃by⁃step balloon dilatation had obvious advantages. Progressive dilatation could be performed by gradient pressure method during operation. The most appropriate dilatation endpoint could be selected. Balloon dilatation within 12 weeks after operation and the second balloon dilatation within 2 weeks after interval improved the dilatation effect of anastomotic stoma. Appropriate increase of dilatation times could improve the quality of life score of patients.

Key words:

DSA, balloon dilatation, esophageal cancer, postoperative anastomotic stenosis ,