关键词:

支气管镜下肺泡灌洗, 支气管扩张并感染, 疗效, suPAR, sTREM?1, CRP ,

Abstract:

Objective To observe the effects of bronchoalveolar lavage under bronchoscope on the efficacy， suPAR，sTREM⁃1 and CRP of bronchiectasis complicated with infection Methods A total of 107 cases of bronchi⁃ ectasis complicated with infection admitted in our hospital from September 2018 to January 2020 were selected. All patients were divided into control group（n = 51）and treatment group（n = 56）. The control group received routine bronchodilation and anti⁃infective therapy，and the treatment group was given bronchoalveolar lavage under broncho⁃ scope on the basis of control group. Results After treatment，the total clinical effectiveness rate of the observation group（94.64%）was significantly higher than that of the control group（76.47%）（P ≤ 0.05）；the levels of FEV1， FEV1/FVC，SaO2 and PaO2 in both groups were significantly higher than those before treatment，and the levels of FEV1，FEV1/FVC，SaO2 and PaO2 in the treatment group were significantly higher than those in the control group （P ≤ 0.05）；the expression levels of suPAR，sTREM⁃1 and CRP in both groups were significantly lower than those before treatment，and the expression levels of suPAR，sTREM⁃1 and CRP in the treatment group were significantly lower than those in the control group（P ≤ 0.05）. Conclusions Bronchoalveolar lavage under bronchoscope could not only effectively enhance the therapeutic effect in patients with bronchiectasis and infection，but also protect lung function，improve the level of blood gas，and reduce the inflammatory reaction，which is of clinical significance. 

Key words:

bronchoalveolar lavage, bronchiectasis with infection, efficacy, suPAR, sTREM ? 1, CRP